Dr. Berne issued a voluntary recall of the Dr. Berne's MSM Drops 5% Solution, while London-based LightEyez Limited has not responded to the FDA or taken actions to protect consumers, according to the agency. London-based LightEyez Limited, maker of LightEyez MSM Eye Drops – Eye Repair (above) has not responded to the FDA warning of a potential "life-threatening infection" from use of the eye drop product, or taken actions to protect consumers, according to the agency. Desideri I, Francolini G, Becherini C, et al. Use of an alpha lipoic, methylsulfonylmethane and bromelain dietary supplement (Opera) for chemotherapy-induced peripheral neuropathy management, a prospective study. Med Oncol. 2017 Mar;34(3):46.View abstract. Richmond VL. Incorporation of methylsulfonylmethane sulfur into guinea pig serum proteins. Life Sci 1986;39:263-8. View abstract. MSM seems to help the body’s natural free radical-scavenging abilities, which means it lowers oxidative stress as well as the many ailments that come along with it. Gumina S, Passaretti D, Gurzì MD, et al. Arginine L-alpha-ketoglutarate, methylsulfonylmethane, hydrolyzed type I collagen and bromelain in rotator cuff tear repair: a prospective randomized study. Curr Med Res Opin. 2012 Nov;28:1767-74. View abstract.

If someone is experiencing any of these symptoms, no matter how mild, I encourage them to seek medical attention immediately,” said Dr. Diane Hilal-Campo, an ophthalmologist and founder of Twenty / Twenty beauty, in an earlier interview with Healthline. A clinical trial testing the effects of MSM supplements on joint pain in 118 patients with osteoarthritis (such as with the knee) found that compared to a placebo, MSM supplements taken over 12 weeks resulted in more improvements in pain, swelling and joint mobility. MSM supplements were given in 500-milligram doses three times daily along with glucosamine (also taken in 500-milligram doses three times daily).According to the 'inventor' of MSM, Dr. Stanley Jacobs, MSM is a "cholinesterase inhibitor. Cholinsterase is an enzyme that stops excessive passage of nerve impulses from one nerve cell to another." The Food and Drug Administration (FDA) has recently recalled three brands of eye drops, including one that has been linked to serious infections, vision loss and a death. UC Davis Health experts share what you need to know.

Update [8/30/2023] Dr. Berne’s Whole Health Products voluntarily recalled Dr. Berne’s MSM Drops 5% and 15% Solution Eye Drops due to bacterial and fungal contamination on August 26, 2023. The remaining MSM exhibits fairly homogeneous tissue distribution and a biological half-life of approximately 12.2 h in rats [ 63]. Tissue distribution in humans is also likely widespread as it has been detected in cerebrospinal fluid and evenly distributed between the gray and white matter of the brain [ 76, 77, 78, 79, 80]. Moreover, the biological half-life within the brain is an estimated 7.5 h [ 79], while the general half-life is suggested to be greater than 12 h [ 65]. The persisting systemic MSM comprises the bioavailable source. Muizzuddin N, Benjamin R. Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing. Int J Vitam Nutr Res. 2020:1-10. View abstract. MSM supplements supply the body with extra sulfur for creating methionine, which helps in important bodily processes like making other chemicals, forming connective tissue, synthesizing/metabolizing foods, and absorbing nutrients to be used for energy. Clear Eyes Once Daily, Eye Allergy Itch Relief: Lot 114349, Lot 117396, Lot 0120128, Lot 114371, and Lot 123781.FDA recommends consumers properly discard these products as FDA describes. Using contaminated eye drops could result in minor to serious vision-threatening infection which could possibly progress to a life-threatening infection. If you take prescription or over-the-counter medications regularly, MSM may affect the way your medications work. It is important to consult with a healthcare provider before taking MSM if you have any underlying health conditions or are taking any medications.

MSM can be produced in a lab, where it is sometimes combined with other supplements such as glucosamine or chondroitin. Why do people take MSM?Other reports show that up to three to six grams of MSM daily (divided into three doses normally) seems to be safe and well-tolerated. In conclusion, while MSM can provide many health benefits, it may not be suitable for everyone. It is important to be aware of the potential risks and consult with a healthcare provider before taking MSM if you have any concerns. If you experience any side effects or have any concerns about taking MSM, it is important to consult a healthcare provider. The Food and Drug Administration (FDA) announced an eye drop recall on November 15 due to safety concerns after investigators found unsanitary conditions.