And that’s where we come in. We believe that your aesthetic age is an investment, worth your hard earned dollars. But you have to be smart about it! We help you do just that.

We assessed all the parameters after 6 weeks and 12 weeks. One of the most interesting results that we got from this study was an improvement in the skin barrier, which happened only on the side of the face that was treated with the OS-01 peptide.” LB: This vision is something that motivates you very personally, and has for quite a long time. It's a passion that we share, including with our audience and the broader longevity movement The first application for the OS-01 peptide that we discovered is to target skin aging and to improve skin health. But eventually, we will test and expand the use of this peptide in other age related conditions. This likely connected to the observable improvements in the overall skin barrier, as discussed in our interview with Carolina.RD: I tell everyone to take a before shot - go out into natural light, with no makeup and a totally relaxed face. Notice what time of day it is and take some photos from the front and from the two sides. So I would say to start by taking pictures, making sure that's you use the same light and same time of the day. Take these every two weeks and every month and compare side by side. It is however, helping to avoid the buildup of senescence cells by promoting cellular repair. Is this correct? Interestingly, the focus of our second part interview with Dr. Carolina Reis, CEO Of OneSkin, is precisely targeted at this question. Can you reverse the age of skin ?

So, while more science is needed to have ‘all the answers’, this is common in the longevity technology sphere. As we look out for our long-term health, we get to choose how far ahead of the ‘proven’ science we individually are comfortable to reach. One Truth 818 Serum is used like most other serums – after cleansing and before moisturising. One Truth 818 is in a gel base and is also incredibly hydrating. It contains macadamia and jojoba oils and esters, bio-compatible phospholipids and Omega’s 3 and 6, so it is very rich in good oils that are absorbed instantly into the skin. Many users report that they don’t need to use a moisturiser, while those with dry skin have simply added it into their routine. It works better than any product I have ever seen in regards to wrinkles around the eye area, reducing and banishing pigmentation and visibly lifting and firming the skin so you may find you can drop the eye cream and other specialists products.LB:On the topic of visual results, your customers love sending you before and after images. If you were to summarise what you have learned from the users of your product, what would you say the most common observations are?

Using OS-01, you can promote skin rejuvenation in a more effective way - from the inside out, instead of the outside in and without the side effects of retinols (redness, dryness, skin sensitization and so on). As Dr Reis pointed out, this is one of the primary drivers of skin aging, and in fact, OneSkin uses UV radiation in the lab to artificially age their 3D human skin equivalents. There's a few ‘anti-aging’ skin products that are pretty popular that I'd like to get you to comment on. Retinoic acid/retinol and hyaluronic acid. OneSkin OS-01 versus Retinol / Retinoic AcidTalk about beauty that is more than skin deep! If we want to maximise healthspan and look out for our longevity, intervening in the aging of our skin is key. It’s natural to wonder, what happens after longer term use of OneSkin? Or was the testing a fluke? Could another factor have been in play? In my last post, I shared three online tools for assessing your biological age. In this follow-up post, I want to discuss another segment of technologies, related to assessing one’s apparent youthfulness. This refers to how old one ‘looks’. In my last post on this topic, I coined the term aesthetic age, so let’s roll with it. Because we are targeting senescent cells – which are a driver of aging in many tissues and the root cause of many age related diseases - we believe we can treat other cells/organs as well. Enhanced with Centella Asiatica, Rosehip Seed Oil, Borage Oil, Orange Peel, Oregano Extract, Vitamin E, Dandelion Extract, Wild Geranium

But in saying that, most of us have had it drummed into us that we need to exfoliate and let’s be honest it feels and looks good short-term. I would recommend staying away from any harsh physical exfoliation products that really damage the skin and just to be aware that there are NO positive benefits to over-exfoliation. IF you can’t give up your exfoliation habits it’s even more important that you use One Truth 818 Serum to counteract the damage you are inadvertently causing. Once you have senescent cells, there is a cascade of inflammatory signals leading to events such as collagen breakdown, which in turn will lead to a series of further dysfunctions in the skin. For the future, we are trying to develop a method that ideally would be non invasive. Perhaps using a tape stripping, where you could collect samples from your skin and we could predict your skin biological age. OneSkin How to Use It

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Because the main harm of senescent cells comes not from the senescence cells themselves, but more from the of inflammatory signaling that spoils the surrounding cells, causing them to age faster. To conduct an effective self-experiment with any skincare regime change, we recommend that you locate some nearby skin clinics and ask them if they operate a Visia Scanner. RD: The atomiser is super hydrating, so if you have problems with hydration, you can pop it on under the serum, and even use it over makeup because it's water based, no oil. Based on our interview with Dr Reis in February, we’d expect there would be observable improvements in skin texture.