Dogs, just like us, can only reach their genetic potential if their diet delivers maximum nutrition. Most commercial dog foods cannot achieve this lofty goal because they are not formulated to do so. What’s more, no one dog food can meet every dog’s individual needs. To enjoy robust health, your dog should receive a high quality vitamin/mineral supplement, alongside essential fatty acids, digestive enzymes, and other nutrients. Wholistic Canine Complete™ accomplishes these goals with one easy-to-use complete supplement. Brown PM, Tzannes S, Nguyen S, White J, Langova V. LOPP chemotherapy as a first-line treatment for dogs with T-cell lymphoma. Vet Comp Oncol. 2018;16:108–13. Within minutes he had everything under control and didn't hesitate to say what the problem was ! And I'm glad he did , even if it was a hard pill to swallow... It was me !!! Ponce F, Magnol JP, Ledieu D, Marchal T, Turinelli V, Chalvet-Monfray K, et al. Prognostic significance of morphological subtypes in canine malignant lymphomas during chemotherapy. Vet J. 2004;167:158–66.

Nerschbach V, Eberle N, Joetzke AE, Hoeinghaus R, Hungerbuehler S, Mischke R, et al. Splenic and hepatic ultrasound and cytology in canine lymphoma: effects of findings on stage migration and assessment of prognosis. Vet Comp Oncol. 2016;14(Suppl 1):82–94.

Moore AS, Cotter SM, Rand WM, Wood CA, Williams LE, London CA, et al. Evaluation of a discontinuous treatment protocol (VELCAP-S) for canine lymphoma. J Vet Intern Med. 2001;15:348–54.

Already early-on, the differentiation between B- and T-cell immunophenotype was shown to possess prognostic value [ 30] and this remains to be the most consistent determinant of outcome supported by numerous clinical studies [ 4, 7, 30, 33, 34, 35]. The presented study again mirrors this important finding, with overall and CR remission durations as well as survival times displaying statistically significant differences independent of other variables between the B- and T-cell lymphomas. There were not many adverse events during this protocol, except for neutropenia. Some 65% of the dogs had one or multiple neutropenic episodes, frequently leading to postponement of treatment. It has been described that there is a higher risk of neutropenia when L-asparaginase and vincristine are given together [ 44]. Other studies found that the timing of administration of L-asparaginase was not directly linked to an increased risk [ 45]. Here we found 24% of the dogs having neutropenia after simultaneous administration of these drugs, however, we also saw 23% of the dogs having neutropenia after single vincristine administration. Therefore, there was no significant increase in neutropenia due to the simultaneous administration and no reason to change the protocol for this adverse event. Wang et al. [ 46] found that dogs with bone marrow suppression that required dose reductions and treatment delays had longer remissions and lymphoma-specific survival times than those requiring no dose reductions or treatment delays. These findings would indicate that chemotherapy-induced neutropenia may be a useful indicator for predicting tumour responses. In our study, however, we could not find this association. Moore AS, London CA, Wood CA, Williams LE, Cotter SM, L’Heureuxet DA, et al. Lomustine (CCNU) for the treatment of resistant lymphoma in dogs. J Vet Intern Med. 1999;13:395–8. He gave so many tips on how to help our dog and gave us the confidence to know we could put things right without making us feel like we were to blame, even though a lot of our dogs behaviour has been fuelled by us without us realising. Ellie our co-manager has the most lovely way with the dogs and produces a lovely full groom etc. to your specification. She is fully qualified and experienced with all types of breeds. We feel we specialise with being able to take the time to deal with nervous or rescue dogs, and Ellie’s calming nature and quiet patience is key to helping these dogs settle and learn to be relaxed about visiting the salon.Piek CJ, Rutteman GR, Teske E. Evaluation of the results of a L-asparaginase-based continuous chemotherapy protocol versus a short doxorubicin-based induction chemotherapy protocol in dogs with malignant lymphoma. Vet Q. 1999;21:44–9. At the time of diagnosis 58 animals (40.3%) were anemic with hematocrit (HCT) ranging from 14 to 39% (median, 35%). Considering all dogs, median HCT was 41% (range, 14–61). Thrombocytopenia at initial presentation was detected in 32 dogs (22.2%) with platelet counts ranging from 24,000–148,000 cells/µL (median, 100,500 cells/µL, normal range, > 150,000 cells/µL). Median number of thromboyctes/µL in all dogs amounted to 247,000. Neutropenia was evident in 3 dogs (2.1%; range, 1320–1970 cells/µL, normal range, > 2000 cells/µL). In 16 dogs (11%), hypercalcemia was apparent (ionized calcium concentration 1.50–2.26 mmol/L; median, 1.78 mmol/L, normal range, < 1.47 mmol/L). I am able to walk them again together with no arguments and Craig has shown me how to be a better and more consistent dog mum too. Set in a quiet and rural location situated on the outskirts of the village of Offord Cluny, we boast plentiful parking and the opportunity of quiet farmland dog walking should you wish to enjoy this facility. Alfie had gotten to the stage whereby he couldn’t be in the same room as his brother without a fight, and by fight, I mean FIGHT!!!

Independent Scientific Writing, Translation & Consultancy Clinical Oncology, Bünteweg 9, Gebäude 280, 30559, Hannover, GermanyWe have tried various other trainers, but to no avail. We have tried positive reinforcement with treats, supplements, sprays, plug ins, CBD.. you name it, we've tried it. Shanti's fear has increased and her behaviour has deteriorated. I also want to personally thank everyone too who has chosen me to help with their dogs both this year and every since I started this (some seven years ago now!), from the mad to the bad and every dog in-between it has been a pleasure so far and I welcome even more of you next year! In total, 173 treatment delays in 83 dogs (65%) (median 1, range, 0–5) were documented, 77% (n = 134, in 67 dogs) of these postponements were caused by neutropenia. The number of neutropenic events was not correlated with DFI (P = 0.804) nor with OS (P = 0.130).