A 1-cup (70-gram) serving of chopped, fresh button mushrooms boasts 5.6 mcg, or 19% of the DV ( 8). Biotin deficiency can also occur in patients on parenteral nutrition without added biotin. [5] [1] [8]Therefore, recommended daily dose of biotin must be added to total parental nutrition (TPN), particularly if TPN therapy is likely to be given for more than a week. Currently, all hospital pharmacies add biotin to TPN preparations. [9] [1]

Biotin Is Required for the Zinc Homeostasis in the Skin - PMC

Zinc benefits the body in so many ways. It aids in nearly every function of the body Natural sources of Zinc Just 3 ounces (75 grams) of cooked beef liver provides nearly 31 mcg of biotin, or 103% of the DV ( 4). It’s also a good source of biotin. Just 1/2 cup (45 gram) of raw, chopped broccoli contains 0.4 mcg, or 1% of the DV ( 4, 8). Let’s take a look at the benefits of biotin and zinc for your hair and overall well-being. Benefits of Biotin Besides iron, zinc is the most common element in the body. The role of zincin the body is vital. Every body cell needs zinc to perform normal chemical reactions.Although a relationship between vitamin D levels and AGA or TE is still being debated, most authors agree in supplementing vitamin D in patients with hair loss and vitamin D deficiency. Vitamin C intake is crucial in patients with hair loss associated with iron deficiency. There are no data to support the role of vitamin E in AGA or TE. A review article on zinc in patients with AA showed that four of the six case–control studies found low zinc levels in patients with AA as compared to healthy control groups [ 55]. One of these case–control studies was conducted by Kil et al. and included patients with MPHL, FPHL, and TE. The results of this study showed a strong correlation between zinc deficiency (< 70µg/dL) and hair loss [ 124]. Another study found a strong association between zinc deficiency and AA severity and chronicity [ 126]. However, in contrast to these studies, there are two case–control studies carried out in Iran [ 111] and Finland [ 113] that showed no significant correlation between zinc level and AA compared to the controls. Canned mushrooms work well over noodles, atop homemade pizzas, and in sauces and gravies, while fresh mushrooms can also be stuffed and baked, sautéed, or added to salads. SUMMARY Don't settle for off the shelf, standard biotin products. Enjoy peace of mind that with Bettervits, The human scalp contains approximately 100,000 hair follicles. Of these, 90% are in the anagen phase, where there is no alopecia, requiring essential elements, such as proteins, vitamins, and minerals, to efficiently produce healthy hair [ 3, 4]. Micronutrients, including vitamins and trace minerals, are therefore crucial components of our diet [ 5]. According to Stewart and Gutherie [ 6], in 1497 Vasco de Gamma recorded the deaths of 100 of his 160 sailors due to scurvy and 300years later James Lind linked scurvy with vitamin C deficiency, noting skin hemorrhage and hair loss [ 6]. In protein-energy malnutrition, skin and hair changes are prominent, as seen, for example in children with kwashiorkor, marasmus, and marasmic-kwashiorkor conditions [ 7]. A severe reduction in carbohydrate intake results in hair loss [ 8].

20 Best Growth Vitamins For Thinning Hair, Per Dermatologists

Zinc is an essential trace element, which means that the body cannot generate it on its own; it must be supplied through the diet. The main dietary sources of zinc are fish and meat. Zinc deficiency can occur in patients consuming large amounts of cereal grain (which contains a phytate considered to be chelating agent of zinc), in those with poor meat consumption or TPN, and in infants on milk formula. Other causes of zinc deficiency include anorexia nervosa (secondary to inadequate intake, increased zinc excretion, and malabsorption due to laxative abuse), inflammatory bowel disease, jejunal bypass surgery, and cystic fibrosis. Alcoholism, malignancy, burns, infection, and pregnancy may all cause increased metabolism and excretion of zinc. Hair loss is a common problem that may be improved with vitamin and mineral supplementation. Vitamins and minerals are important for normal cell growth and function and may contribute to hair loss when they are deficient. While supplementation is relatively affordable and easily accessible, it is important to know which vitamins and minerals are helpful in treating hair loss. Three groups of molecules hydrolyze ATP, namely, ENTPDs, ectonucleotide pyrophosphatase/phosphodiesterases (ENPPs), and alkaline phosphatase (ALP) [ 33, 34]. The latter two molecules are zinc-dependent molecules. Among ENTPDs and ENPPs, ENTPD-1 (CD39), -2, -3, and -8 and ENPP-1, -2, and -3 hydrolyze ATP [ 33]. LCs strongly express ENTPD-1 (CD39) and weakly express ENTPD-2 and ENPP-1, -2, and -3. KCs weakly express CD39, ENTPD-2 and -3, and ENPP-1 and -2 [ 16]. Neither LCs nor KCs express ENTPD-8 or ALP. Therefore, although LCs strongly express CD39, other ATP-hydrolyzing molecules are weakly expressed in both LCs and KCs. LCs occupy approximately 3% of the epidermis, whereas KCs occupy approximately 97%. Regardless of this numeric difference between LCs and KCs in the epidermis, LCs perform approximately 80% of epidermal ATP hydrolysis, whereas KCs perform the remaining 20% [ 16]. Additionally, ZnD impairs the activity of ENPPs [ 35]. KCs weakly express ENPP-1 and ENPP-2. This explains one underlying mechanism by which ZD–KCs and BD–KCs show increased ATP production.In contrast to the study of Gowda et al. [ 109], a study conducted by Deo et al. in India aimed to detect the prevalence of several forms of hair loss in females and to correlate these data with levels of hemoglobin and serum ferritin. This observational study involved 135 subjects, the majority (62.2%) of whom had TE, with the next largest group having FPHL (23.7%). Neither low hemoglobin (<12gm%; 73.4%) nor low serum ferritin (<12μg/L; 6.7%) levels were found to be statistically significant [ 110]. The role of essential amino acids in anemia is well known, but just how amino acids affect iron uptake is the subject of ongoing research. Also, the possible impact of amino acids on hair growth has yet to be elucidated. The bioavailability of l-lysine is restricted primarily to fish, meat, and eggs. Little is known about the influence of l-lysine on iron uptake and utilization. In one study, some of the participating women achieved a modest increase in serum ferritin level after iron supplementation, i.e., supplementation with elemental iron 50mg twice daily; adding l-lysine (1.5–2g/day) to their existing iron supplementation regimen resulted in a significant ( p<0.001) increase in the mean serum ferritin concentration [ 85]. Biotin is a water-soluble vitamin that serves as a co-enzyme for five carboxylases, namely, the covalently bound coenzyme for acetyl-CoA carboxylases 1 and 2, pyruvate carboxylase, propionyl-CoA carboxylase, and 3-methylcrotonyl-CoA carboxylase. These biotin-dependent carboxylases facilitate various metabolic reactions such as gluconeogenesis, fatty acid synthesis, and amino acid synthesis. Mammals cannot synthesize biotin by themselves; they obtain biotin through food and some gut microbiota produce biotin. Biotin deficiency (BnD) rarely occurs in people who consume a normal mixed diet [ 1, 2]. However, genetic deficiency of holocarboxylase synthetase and biotinidase, continuous consumption of raw egg whites, parenteral nutrition, and modified milk without biotin supplementation could result in BnD [ 1, 2, 3]. Patients with BnD [ 4] are known to develop clinical symptoms that are similar to those in patients with acrodermatitis enteropathica (AE), which is caused by loss-of-function mutations in Zrt-, Irt-like protein (ZIP) 4 [ 5, 6, 7]. The clinical symptoms of AE include characteristic skin lesions, alopecia, and diarrhea. A 1/2-cup (125-gram) serving of cooked sweet potatoes contains 2.4 mcg of biotin, or 8% of the DV ( 4). Exogenous biotin interferes with some laboratory tests, creating false negative or false positive results

The Role of Vitamins and Minerals in Hair Loss: A Review

Nuts and seeds are a good source of fiber, unsaturated fat, and protein. Most also provide biotin, but the amount tends to vary by type ( 10).

A clinical trial in patients with ovarian cancer undergoing chemotherapy showed a significant decrease in hair loss and other gastrointestinal symptoms in patients receiving selenium supplementation, as compared with controls. The authors concluded that ingesting selenium is a supportive element in chemotherapy [ 119]. Vitamin A represents a group of fat-soluble retinoids that includes retinol, retinal, and retinyl esters [ 11, 12]. This vitamin serves many roles in the body: it is critical for vision, involved in immune function, and is necessary for cellular growth and differentiation [ 13]. Vitamin A exists in the diet as preformed vitamin A (from animal sources) and as provitamin A carotenoids (sourced from plants). Both sources of vitamin A must be metabolized intracellularly to their active forms (retinal and retinoic acid). The majority of vitamin A is stored in the liver as retinyl esters. When measuring retinol and carotenoid levels, plasma levels are typically sufficient for determining adequacy. A plasma retinol concentration of < 0.70 μmol/L signifies vitamin A inadequacy [ 13]. Research shows that biotin (also known as vitamin B7) is a key hair vitamin. As well as contributing to normal hair and skin, biotin also contributes to normal metabolism functioning. Carefully chosen to work together, zinc complements biotin as it also contributes to normal hair and skin. This essential mineral also contributes to the normal function of the immune system, metabolism and healthy nails. Formulated for hair, skin and nails

Biotin with Zinc - 180 Tablets - SuperSelf Nutrition Biotin with Zinc - 180 Tablets - SuperSelf Nutrition

Crider K, Williams J, Qi YP, Gutman J, Yeung L, Mai C, Finkelstain J, Mehta S, Pons-Duran C, Menéndez C, et al. Cochrane Database Syst Rev. 2022 Feb 1; 2(2022). Epub 2022 Feb 1. At Particle, our focus is on providing the best products with premium ingredients to enhance men’s health. Let us help you look and feel your very best. Symptoms of zinc deficiency include thinning hair, acne, stunted growth, diarrhea, loss of appetite, and eye and skin lesions. There’s some indication that weight loss, slow wound healing, mental exhaustion, and an abnormal sense of taste could be due to zin deficiency. Getting adequate amounts of biotin in the food you eat or through supplements may may contribute to healthier hair, stronger nails, and softer skin. More recently, a cross-sectional study conducted by Gade et al. sought to assess serum vitamin D levels in patients with AA as compared to healthy controls, and to further identify the association between vitamin D levels and disease severity in patients with AA. The study included 45 adult patients with AA and 45 control subjects. Serum vitamin D was estimated using enzyme-linked immunosorbent assay (ELISA) kits. The severity of AA was determined using the Severity of Alopecia Tool (SALT) score. The mean vitamin D level was found to be significantly lower in patients with AA (17.86±SD 5.83ng/mL) than in the healthy controls (30.65±SD 6.21ng/mL) ( p=0.0001). The level of vitamin D showed a significant inverse correlation with disease severity ( p=0.001) [ 70].Eggs are full of B vitamins, protein, iron, and phosphorus. The yolk is an especially rich source of biotin ( 5). Legumes like peas, beans, and lentils are high in protein, fiber, and numerous micronutrients. Some of the richest sources of biotin in this category are peanuts and soybeans ( 7). A whole, cooked egg (50 grams) provides approximately 10 mcg of biotin, or approximately 33% of the DV ( 4). Some of the best sources of biotin include legumes, egg yolks, organ meats, nuts, seeds, mushrooms, avocados, sweet potatoes, and yeast.