With Nordic Naturals B-Complex, you'll get a dose of all eight B vitamins, ranging from 83% to 10,417% of your daily needs. Nordic Naturals prioritizes the forms of the vitamins that are activated and more readily absorbed by your body. It’s used more frequently in supplements, as it’s considered more stable and cost effective than other forms of vitamin B12. Excess folic acid. Taking more than 1,000 mcg of folic acid a day can mask a type of anemia caused by vitamin B12 deficiency. Nutrilite Vitamin B Dual Action is a great supplement to take to ensure you are getting adequate B vitamins in your diet, without providing too much above the recommended intake.

You can get many of the nutrients you need as a vegan or vegetarian from food sources. But doing so takes extremely careful planning—and getting certain nutrients,such as B vitamins and iron,is much more difficult if you don’t eat meat, poultry, or seafood. Liu, H.-L., et al. (2015). The effectiveness of vitamin B12 for relieving pain in aphthous ulcers: A randomized, double-blind, placebo-controlled trial [Abstract]. As you age, your ability to absorb vitamin B12 decreases and your appetite declines, making it difficult for some people to get enough B12 through diet alone.B vitamins have a wide range of functions, including enabling the release of energy through metabolism and supporting the nervous system. Low levels of B vitamins can lead to neurological and physical problems. Behrens, A., Graessel, E., Pendergrass, A. et al. Vitamin B—Can it prevent cognitive decline? A systematic review and meta-analysis. Syst Rev 9, 111 (2020). https://doi.org/10.1186/s13643-020-01378-7 B vitamins may also enhance treatment response when given in combination with antidepressant medication. Separately, as of November 2022, the FDA prohibits nicotinamide mononucleotide (NMN) to be sold as a supplement while they investigate its potential usage as a drug. Because this mandate is new, you will likely still see this ingredient on the market until the regulation is fully enforced. The B-complex vitamins we recommend in this article do not contain nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN).

The third-party certifications we can trust are: ConsumerLab.com, NSF, and USP. However, these certifications are difficult to obtain and/or expensive for manufacturers, so many companies choose not to get their products tested by one of these three organizations. A wide and complex variety of B vitamins is essential for the body to convert food into cellular energy. These water-soluble groups of vitamins are first absorbed in the small intestine and then travel to the liver where they are biotransformed into their active coenzyme forms. One of the key roles of B vitamins is to serve as prime coenzymes for the Kreb’s cycle, the biochemical pathway responsible for maintaining energy production. In addition, B vitamins, particularly folate, B6 and B12, are critical for proper methylation, a biochemical process that helps convert the problematic amino acid metabolite homocysteine into the amino acids methionine and cysteine. This process is vital for supporting cardiovascular and mental health, a healthy nervous system, regulating gene expression, proper energy metabolism, as well as immune and nerve cell function. Additional intake of B vitamins is often needed by individuals with high levels of stress.

A study in 60 adults with depression showed that treatment with a vitamin B complex for 60 days led to significant improvements in depression and anxiety symptoms, compared with a placebo ( 29).

Additionally, the MTHFR genetic mutation can affect how your body metabolizes folate, which can lead to a folate deficiency and other health concerns ( 21). This might be a great supplement choice if you are vegan or vegetarian, and that's not just because it's certified vegan. Our bodies absorb only about 1% of the B12 we get from supplements, and the main food sources of B12 are animal foods. Because of this, nutrition experts recommend that vegans supplement with over 10,000% of the daily value of vitamin B12 each day and that vegetarians who eat dairy and eggs take this amount of B12 a few times per week. Nordic Naturals B-complex provides this exact amount of B12. This nutrient is important for supporting many biochemical reactions within your body, including interactions with your hormones and neurotransmitters. It also plays a role in the healthy production of hemoglobin (where a lot of the iron in your body is stored). Arévalo, S. P., et al. (2018). Vitamin B6 and depressive symptomatology, over time, in older Latino adults.

Vitamin B12

For example, proton pump inhibitors, which are medications that lower stomach acid, can decrease the absorption of B12, whereas metformin, a popular diabetes drug, can decrease levels of both B12 and folate ( 24, 25). One thing to keep in mind: Supplements aren’t regulated by the Food and Drug Administration (FDA), so you should only buy from a trusted, reputable brand. This helps ensure you’re taking a high quality product without any questionable additives.

Rembe, J.-D., et al. (2018). Effects of vitamin B complex and vitamin C on human skin cells: Is the perceived effect measurable? [Abstract]. Methyl Complex also contains vitamin B12 as methylcobalamin, which is the activated, body-ready form of vitamin B12. The importance of adequate levels of B12 cannot be understated. B12 is involved in several important functions in the body, within every single cell! Vitamin B12 is also essential for normal homocysteine metabolism. In the body, the remethylation of homocysteine is dependent on adequate levels of vitamin B12.For the first decade or so of my vegetarianism—long before I even thought about becoming a registered dietitian—I had absolutely no idea what I was supposed to be eating or which supplements I should consider.