Comparison of the outcome (in terms of mean healing time) of amnion versus conventional antimicrobial ointment alone in facial burn patients: a randomised control trial MEBO regenerative nutritional substance for skin can protect, regenerate and nourish all layers of skin tissue cells in a three-dimensional way. MEBO skin care products use soluble fatty acids as the oil-phase base material, which is a breakthrough in cosmetic products. They have excellent skin-friendly moisturizing property, and more importantly, under their nourishment, fibroblasts will present fasciculate arrangement to support skin, showing a healthy and tight skin status. More > Pain (procedural pain, during wound care): I1: 1.3 (SEM 0.3); I2: 1.6 (SEM 0.5), reported P = 0.59. Bioactive skin substitute (a bilayered, biologically active, temporary skin substitute (TransCyte)) vs antibacterial ointment, not specified

Dropout not described, number of participants in follow‐up not provided in text or in table 3, discrepancy time to complete wound healing data between text and table 3.

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Relatively high dropout rate in study. No information on reasons long‐term dropouts at patient level, substantial dropout.

It has remarkable properties of adhesiveness ,permeability,emulsification and smoothness due to its unique perparation structure, and thusit can form a natural protective barrier on the surface of scars and is suitable for the treatment of various scars resulting from burns,scalds,traumas ,surgical acne and cosmetic-induced skin damage,etc. More > Third degree bums, to isolate the wound, reduce pain, and expedite nonsurgical debridement of the necrotic tissue to prepare the wound for grafting. comparator intervention: type of dressing, dose used, frequency of dressing changes, time elapsed before treatment, concurrent interventions; Although originally described as idiopathic, FG has an identifiable cause in almost 95% of cases. The necrotizing process commonly originates from an infection in the anorectum, the urogenital tract, or the skin of the genitalia.

As‐treated' analysis done with substantial departure of the intervention received from that assigned at randomisation. Moderate certainty: we are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Beta-sitosterol 0.25%. The base of the ointment is composed of sesame oil and beeswax, 18 amino acids, 4 major fatty acids, vitamins and polysaccharides. face OR facial OR nose OR ear OR ears) AND burns [Title] AND topical OR local OR ointment OR dressing OR bandage OR lotion OR cream OR gel OR solution [Interventions] MEBO Acne Clear cleanses irritated and infected skin and helps the skin’s defense against bacteria. It also nourishes and protects the skin. More >

Blinding of participants and key study personnel ensured, and unlikely that the blinding could have been broken. Comparison 4: Miscellaneous treatment versus miscellaneous treatment, Outcome 1: Time to wound healingTwo review authors (CH and MvB) independently extracted and summarised details of trials using a data extraction sheet. To provide independent data extraction, a third person (Inge Spronk) not involved in one included study, performed data extraction and risk of bias assessment of the study from Oen 2012, together with CH. Data from a paper in the Chinese language was extracted by a member of Cochrane Wounds. We extracted data on the following items: Two review authors (CH and MvB) independently assessed the titles and abstracts of these records and judged 21 records from 18 studies to be potentially eligible for the review. MEBO is of natural and herbal edible O(lgln, It IS composed of B·sitosterol 0.25% as the main active ingredient. The base of the Ointment IS composed of sesame oil and beeswax. tn addition to that, MEBO includes In Its formula 18 amino acids. 4 major fatty acids, vitamins. and polysaccharides. MEBO burn repair helps clear away toxic material and promotes the natural repair and regeneration of new skin.

For dichotomous outcome data, the proportion of missing outcomes compared with observed event risk not enough to have a clinically relevant impact on the intervention effect estimate. Insufficient reporting of attrition/exclusions to permit judgement of low or high risk of bias (e.g. number randomised not stated, no reasons for missing data provided).

First Aid for burns injury MEBO Burn and Wound Ointment application

characteristics of the trial: method of randomisation, setting, location of care, country, source of funding; S45 TI dressing* or pad or pads or gauze or tulle or film or bead or foam* or non‐adherent or non adherent or hydrocolloid* or hydrofibre* or hydrogel* or alginate* or plaster* or compress or absorb* or dextra* or silicon* or amnion* lsolafing and protecting the wound bed from environmental factors but at the same time maintaining drainage and gaseous exchange. face OR facial OR nose OR ear OR ears) AND burn [Condition] AND topical OR local OR ointment OR dressing OR bandage OR lotion OR cream OR gel OR solution [Interventions]