In fact, it’s so potent that some studies have shown it to match the power of some anti-inflammatory drugs, without the negative side effects ( 12, 13, 14). Protective effects of piperine on the retina of mice with streptozotocin-induced diabetes by suppressing HIF-1/VEGFA pathway and promoting PEDF expression“.Int J Ophthalmol. 2021. High blood cholesterol is associated with an increased risk of heart disease, which is the leading cause of death worldwide ( 27, 28). Free radicals are unstable molecules that can damage your cells. Some free radicals are created naturally — such as when you exercise and digest food. Curcumin’s anti-inflammatory properties are often praised for reducing pain and temporary discomfort.

But this spice acts quite similarly to the rest of human existence: fractally. The more you zoom in and learn about it, the more you find out there remains to be learned.Digestive stimulant action of three Indian spice mixes in experimental rats“. Central Food Technological Research Institute, Mysore, India. 2002 December. Antioxidants are compounds that fight cellular damage caused by unstable molecules called free radicals. Kannappan R, Gupta SC, Kim JH, Reuter S, Aggarwal BB. Neuroprotection by spice-derived nutraceuticals: you are what you eat! Mol Neurobiol. 2011;44(2):142-159. doi:10.1007/s12035-011-8168-2 PMID:21360003

Toss the drained pasta into the leek pan, then remove from the heat and wait 2 minutes for the pan to cool slightly while you finely grate the cheese and beat it with the egg (if the pan’s too hot, it’ll scramble; get it right and it’ll be smooth, silky and deliciously elegant). A 14-day study in healthy adults found that taking 15 mg of beta-carotene with 5 mg of piperine substantially increased blood levels of beta-carotene compared to taking beta-carotene alone ( 15). May Promote Digestion and Prevent DiarrheaThis, in turn, aids in the breakdown of food and eases the digestive process, reducing the likelihood of digestive discomfort. Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats“. Raval College of Pharmacy, India. 2011 May.

Bang JS, Oh DH, Choi HM, et al. Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models. Arthritis Res Ther. 2009;11(2):R49. doi:10.1186/ar2662 PMID:19327174 Place the Wedges into the basket. Shake half way through cooking. Cook until they’re lovely crisp and light golden.Enhanced Nutrient Absorption: Piperine inhibits certain enzymes that break down nutrients, giving the body more time to absorb essential vitamins and minerals. Whether it’s a creamy Alfredo sauce or a savory pan gravy, the spice harmonizes with other ingredients, creating a well-balanced and memorable sauce that complements the main course.