The true benefit of our products is often seen with prolonged use. We recommend using our products for 7-10 days so that the product has time to moisturise and penetrate the nourishing ingredients through all the skin layers. Research suggests that the effects of colloidal silver vary depending on the size and shape of the particles of silver, as well as their concentration in a solution ( 8, 9, 10, 11). We can offer the entire Clarol skincare kit at a reduced price because it means that customers buy several products at once so we can then factor in the reduced postage costs and reflect that in a price reduction of all the products.

The biggest risk associated with chronic exposure to colloidal silver is a condition known as argyria, whose name comes from the Greek word “argyros,” meaning silver. The real risks of ingesting silver nanoparticles, which are present in colloidal silver products, are also unknown. However, since these particles may easily pass into various organs like your gut, skin, or lungs, they’re considered a probable health risk ( 11). Absorption of silver sulfadiazine varies depending upon the percent of body surface area and the extent of the tissue damage. Although few have been reported, it is possible that any adverse reaction associated with sulfonamides may occur. Some of the reactions, which have been associated with sulfonamides, are as follows: blood dyscrasias including agranulocytosis, aplastic anemia, thrombocytopenia, leukopenia, and hemolytic anemia; dermatologic and allergic reactions, including life-threatening cutaneous reactions [Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and exfoliative dermatitis]; gastrointestinal reactions; hepatitis and hepatocellular necrosis; CNS reactions; and toxic nephrosis.You’re environmentally exposed to extremely small amounts of silver every day. It’s present in very tiny amounts in drinking water, the food supply, and even the air you breathe ( 8). Lab-tested, safety assessed and fully compliant with EU cosmetic regulation 1223/2009. Vegan friendly and absolutely not tested on animals. Looking to treat your furry friend? The benefits of Colloidal Silver can be used on animals too. See our Animal Range here. AM: Clarol Pore Minimising Toner + Silver Serum ( if using make up apply this before any make up is applied) + Clarol Primer ( if using make up apply this before any make up is applied) The most common side effects are a burning sensation, itching or rash around where the cream is applied. Silver Antimicrobial Dressings in Wound Management: A Comparison of Antibacterial, Physical, and Chemical Characteristics— Medscape Wounds

Enhanced with the antibacterial and skin healing properties of Colloidal Silver, our healing yet luxurious and smooth hand cream is a year-round skin saviour that really helps to repair skin fast. Unlike any other hand cream, we've loaded ours with antifungal and antiviral natural ingredients so skin is protected when used daily and treated and repaired at the first sign of irritation. Any company that produces silver products that are labeled or promoted to prevent or cure disease must undergo FDA approval prior to marketing. Otherwise, the product is considered misbranded and is subject to regulatory action ( 3). Remove make up as soon as possible when getting in after the day’s events. Even if you are going out in the evening try to remove day make up as it will be contaminated with dirt and bacteria. Re applying clean make up for evening wear.

While argyria isn’t inherently harmful, it’s irreversible and likely permanent. That said, since little research is available on the side effects of colloidal silver, there may be other unknown side effects. Biofilm is especially difficult to treat, because it enhances bacterial recalcitrance to antimicrobials. This is due to molecules within the extracellular polymeric substance of the biofilm that interfere with antibiotic function 25 or physically shield the bacteria. 26 One strategy to combat biofilm and jumpstart healing is by disrupting the biofilm and displacing the bacteria into a planktonic (rather than sessile) state, where they are more susceptible to systemic antibiotics. This can be achieved with sharp debridement of the wound. However, even with adequate debridement, even a few remaining bacteria can recreate the biofilm within 48 hours. 27

While the silver ion has great antimicrobial and bactericidal properties, it is also toxic to fibroblasts when present in high concentration. 1, 16, 17 Injudicious use of silver-containing dressings can lead to impaired wound healing. 45 It is imperative, therefore, that guidelines be developed on the proper use of silver-containing dressings. Don't use other medicines on the same area of skin as Flamazine cream unless your doctor, nurse or pharmacist say it's OK. Silver has been known to have bactericidal properties and it has been at the core of many studies for several years (5). Silver recently gained renewed attention in the treatment of bacterial infection and prevention of wound sepsis in different prescription forms in conjunction with other materials such as wound dressings impregnated with silver salts or metal nanoparticles 6, 7, 8. One of the silver products that is increasingly being used to cover burn wounds, traumatic injuries, skin graft, diabetic ulcers, incisions, abrasions and minor cuts are silver dressings (9). Metallic and ionic silver was used in a variety of medicinal and medical devices such as topical creams, emulations, catheters and medical prostheses 10, 11, 12, 13, 14, 15. However, different methods have been used to impregnate wound dressings with silver compound, but coating a textile, fibre or polymer mesh with a layer of nanocrystalline silver resulted in sustained release and long‐acting antibacterial wound dressings 9, 16. In 1998, Tredget et al. (17) showed the safety and efficacy of a nanocrystalline silver‐coated polyethylene mesh in preventing infection in burn wounds by reducing the bacterial burden. Although the anti‐inflammatory mechanism of nanocrystalline silver is not clear (13), it might reduce inflammation by fighting the bacterial infection (18)– an important reason for persistent inflammation which leads to infiltration of neutrophils and elevated matrix metalloproteinases (MMPs) in infected wounds. MMPs play a role in the controlled degradation of the extracellular matrix. It has been shown that nanocrystalline silver and its derivative solution have anti‐inflammatory effects; for instance, a study suggested that the level of MMPs is reduced in the presence of nanocrystalline silver dressings; elevated activities of these enzymes may lead to excessive extracellular matrix destruction. Also, nanocrystalline metallic silver dressings can suppress MMP‐9 activity and reduce TNF‐ α levels in the wounds 19, 20, 21. Pain, burning, or itching of the treated skin may occur. Skin and mucous membranes (such as the gums) may become blue/gray in color. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Silver-coated polyurethane NPWT sponge achieves a larger zone of bacterial inhibition than plain polyurethane spongeCompare healing with nanocrystalline silver versus non-silver-containing dressings for lower-extremity venous ulcers A smaller number of people go as far as to assert that it helps treat conditions like Lyme disease, tuberculosis, HIV, and even cancer. However, no research supports these claims. Medicines and their possible side effects can affect people in different ways. The following are some of the side effects that may be associated with Flamazine cream. Just because a side effect is stated here doesn't mean that all people using this cream will experience that or any side effect. A major issue is the misinterpretation of the results from test-tube and rodent studies. Although a study may suggest that colloidal silver kills certain strains of bacteria in a lab setting, this finding can’t be applied to humans ( 8).

Tell your doctor right away if you have any serious side effects, including: signs of infection (such as sore throat that doesn't go away, fever, chills), easy bruising/bleeding, signs of anemia (such as unusual tiredness/ weakness, rapid breathing, fast heartbeat), signs of kidney problems (such as change in the amount of urine, pink/bloody urine), signs of liver problems (such as nausea that doesn't stop, stomach/ abdominal pain, vomiting, dark urine, yellowing eyes/ skin), mental/mood changes. Additionally, silver is commonly added to bandages and dressings to help with wound and burn healing. Common brands names include Acticoat, Allevyn Ag, Aquacel Ag, Biatain Ag, Flamazine, Mepilex Ag, and Silvercel ( 7). Flamazine cream should not be used on leg ulcers or pressure sores that are producing a lot of discharge.Compare activity of polyurethane NPWT sponge versus silver-coated polyurethane NPWT sponge against S. aureus and S. epidermidis SSD contains silver, glycols, alcohols, and sulfadiazine (an antibiotic). 1 SSD has been found to release an extremely high initial silver concentration into the wound (up to 3,176ppm), 17 which rapidly decreases to below therapeutic levels. SSD can therefore have high local toxicity, without providing the sustained silver levels necessary for microbicidal activity. In addition, propylene glycol, which is part of the SSD formulation, is known to cause bone marrow toxicity and leukopenia. 5, 18 Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). The person applying silver sulfadiazine to burn wounds should wear sterile disposable gloves. Take care to keep the treatment area as clean as possible to prevent further infection.