The magic of the Encanto has blessed every child in the family with a unique gift from super strength to the power to heal—every child except one, Mirabel. On the evening of the proposal, Isabela sits in between Mariano and Mirabel, and often glares at Mirabel when she speaks. Isabela becomes visibly confused when Mirabel and Agustín try to hurry Mariano along and get him to propose faster. She gets irritated when Mirabel interrupts Mariano's proposal, but as he's proposing Isabela has a forced smile on her face.

Dolores Madrigal: Dolores is Isabela's younger cousin by a few weeks. Being older than her, Isabela overshadowed Dolores all her life and left her in her shadow. Although their relationship is described as complicated, in the film both are very close and it is clear that they love each other very much. Isabela is not very affectionate with her family for most of the film, but she proves to be very affectionate with Dolores from the beginning and even treats her as if she were her own younger sister. During Antonio's gift ceremony, Isabela is seen holding Dolores's hand while hugging her reassuringly for most of the ceremony. In the song " All of You", Isabela is noticeably excited and happy for Dolores when she proclaims her feelings for Mariano and they become a couple. https://thedisinsider.com/2020/12/09/exclusive-new-details-for-walt-disney-animation-studios-encanto/When the dinner is ruined and everyone leaves the dining room, Isabela walks past Mirabel and proclaims that she hates her.

Mariano Guzmán: Mariano was initially Isabela's soon-to-be fiancé by the will of her grandmother Alma. Although she does not treat him badly, Isabela never loved Mariano nor was she interested in him. In " The Family Madrigal", Isabela does not even look at Mariano when Mirabel sings about him and gets angry with Camilo when he shapeshifts Mariano, showing from the beginning that Isabela had a hard time accepting that she had to marry the man. During the dinner proposal, Isabela was nice to Mariano, but had a visibly forced smile on her face during his proposal due to her unhappiness with the arrangement, and the fact that she doesn't want to marry him, something that she didn't show to anyone except her youngest sister Mirabel. She also broke his nose twice, once during the proposal, and the other during " What Else Can I Do?", and saying that his nose looks like a smashed papaya during her argument with Mirabel, before she asked her if she has lost her mind. Despite having a slight dislike for Mariano, Isabela seems to still recognize Mariano is a good guy and at least someone to be friends with, even though she doesn’t want to marry him. At the party in Antonio's new room, she dances and chatting amiably with Mariano during " All of You", she was happy when Mariano fell in love with her cousin Dolores and became a couple with her. At one point, Isabela had a dorky suitor named "Bubo Marquez", with whom she would elope, leaving the Encanto. But this was eventually scrapped as the staff took Isabela's character to a new direction which didn't involve a man. [5] [4] Being the first grandchild of the Madrigals, she is described as the "golden child" of the family due to her grace, beauty, and gift.Sometime the next morning, Isabela joined the rest of her family for breakfast, and Alma announces that he spoke with the Guzmáns about Mariano's proposal to Isabela. Throughout the conversation, Isabela is visibly nervous about the prospect of getting married to Mariano, especially when Dolores comments that Mariano wants five babies which makes Isabela sprout nervous flowers on her head. Antonio Madrigal: Antonio is Isabela's younger cousin. Isabela wanted Antonio's gift ceremony to go well and decorated the entire Casa Madrigal with flowers for her cousin's special day. During the ceremony, Isabela waved her hands in a jump of joy when her cousin received her gift. After Mirabel interrupted Antonio's gift ceremony, Isabela looked at her sister with a lot of anger because she thought she was envious of Antonio's successful ceremony and wanted to ruin the day. In the family photo at the end of the film, Isabela was happily trying to get closer to her cousin. https://www.etonline.com/media/videos/diane-guerrero-believes-encanto-character-isabela-is-gay-hopes-to-explore-in-sequel According to the books Disney Encanto: The Deluxe Junior Novelization and Disney Encanto: A Tale of Three Sisters: [6] [7]