Kumar MS, Jaiprakash B Hukkeri VI. Preventive effect of Phyllanthus amarus on prostatic hyperplasia. Hamdard Medicus 2006;114-117.

Ranilla LG et al. Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs and spices in Latin America. Bioresour Technol. 2010 Jun;101(12):4676-89. In other studies on rabbits, rats, and cells, chanca piedra reduced blood pressure, prevented excessive platelet clumping, relaxed blood vessels, and improved heart function [ 67, 68, 69, 70, 71]. Foo LY. Amariin, a di-dehydrohexahydroxydiphenoyl hydrolysable tannin from Phyllanthus amarus. Phytochemistry 1993;33(2):487-491. Kidney stones are deposits of minerals and salts that build up in the kidneys or urinary tract. In clinical studies with over 200 people with kidney stones, chanca piedra ( Phyllanthus niruri) reduced their kidney stones, helping to clear the minerals and salt deposits [ 21, 22, 23, 24, 25, 26]. Excesso de fertilizante. O uso excessivo de fertilizantes pode impedir que as plantas absorvam água, levando ao ressecamento.

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Chatterjee, M. and Sil, P. C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. Indian J Biochem Biophys. 2006;43(5):299-305. View abstract. Myint MM, Than MA Lwin KK et al. Preliminary study on hypoglycemic effect of Phyllanthus niruri Linn. (Taung-ze-phyu) on rabbit model. Myanmar Health Sciences Research Journal 2009;17-21. Lee NYS et al. The pharmacological potential of Phyllanthus Niruri. J Pharm Pharmacol. 2016 Aug;68(8):953-69.

No evidence supports the use of chanca piedra for any of the conditions listed in this section. Below is a summary of the existing animal and cell-based research, which should guide further investigational efforts. However, the studies listed below should not be interpreted as supportive of any health benefit. Infections Notka, F., Meier, G. R., and Wagner, R. Inhibition of wild-type human immunodeficiency virus and reverse transcriptase inhibitor-resistant variants by Phyllanthus amarus. Antiviral Res 2003;58(2):175-186. View abstract. Its use in Ayurvedic traditional medicine is well-documented. In Ayurveda, chanca piedra has been used for [ 1, 5, 9, 10]: Londhe, J. S., Devasagayam, T. P., Foo, L. Y., and Ghaskadbi, S. S. Antioxidant activity of some polyphenol constituents of the medicinal plant Phyllanthus amarus Linn. Redox.Rep. 2008;13(5):199-207. View abstract.The name “Quebra Pedra” is Portuguese and translates to “ stone breaker” or “shatter stone,” which reflects its traditional use as a natural remedy for kidney stones and gallstones. Here are some key points about it: Rao, M. V. and Alice, K. M. Contraceptive effects of Phyllanthus amarus in female mice. Phytother.Res 2001;15(3):265-267. View abstract.