In cases such as these, administer a double dose of Anxitane 3 to 4 hours in advance. Anxitane dosage For optimal results, consider using an ADAPTIL Collar. This products ensures your dog is benefiting from the soothing effect wherever they are. Specifically for puppies, ADAPTIL Collar Junior comforts newly adopted puppies and helps facilitate their learning. Song CH, Jung JH, Oh JS, Kim KS. Effects of Theanine on the Release of Brain Alpha Wave in Adult Males. Korean J Nutr. 2003;36(9):918–23 [Korean]. The risk is increased in dogs with hypotension or when L-theanine is given with drugs which reduce blood pressure. Pike AL, et al. An open-label prospective study of the use of l-theanine (Anxitane) in storm-sensitive client-owned dogs. J Vet Behav: Clin Applications Res. 2015;10(4):324–31.

Another choice is Anxitane, a highly palatable, chewable tablet from Virbac. This non-drowsy chew contains the natural ingredient L-Theanine, which helps to calm and reduce anxiety in dogs and cats. It has a fishy flavour, making it that little bit easier to give to your pet. Unno T, Suzuki Y, Kakuda T, Hayakawa T, Tsuge H. Metabolism of theanine, gamma-glutamylethylamide, in rats. J AgricFodd Chem. 1999;47:1593–6. Nathan PJ, Lu K, Gray M. The neuropharmacology of L-theanine (N-Ethyl-L-Glutamine): a possible neuroprotective and cognitive enhancing agent. J Herb Pharmacother. 2006;6(2):21–30. Anxitane is supported by science – extensive number of scientific papers available which speak about the efficacy of L-Theanine Mills DS, Redgate SE, Landsberg GM. A meta-analysis of studies of treatments for feline urine spraying. PLoS One. 2011;6(4):e18448.Kobayashi A, Nagato Y, Aoi N, Juneja LR, Kim M, Yamamoto T, Sugimoto S. Effects of l-theanine on the release of α-brain waves in human volunteers. Nippon Nogeikagaku Kaishi. 1998;72:153–7. Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007;74(1):39–45.

Anxitane is a flavoured, nutritional supplement that has a calming effect on dogs and cats. Anxitane is ideal to help your pet deal with stressful situations! Gagnon AC, Chaurand JP, Larue JF. Le comportement du chat et ses troubles. Maisons-Alfort: Editions du point vétérinaire; 1995. p. 288. All the parameters significantly improved (lower score) during the course of the study, except for those which concerned too few animals (< 4 cats: diarrhoea, hypersalivation and redirected aggression). Hypervigilance/hyperesthesia was the parameter with the highest median score at D0 and concerned 27/33 cats (82%). A significant decrease of this median (IQR) score was observed during the course of the study: from 3 (2–3), to 1 (0–2) and 1 (0–1) at D0, D15 and D30 respectively ( p< 0.0001). At the end of the study, 8/27 cats (30%) no longer showed the signs. Shivering was the parameter most reduced in frequency since it was detected in 11/33 cats (33%) at the beginning of the trial and in only 3/33 cats (9%) by the end of the study.

Almost all of the parameters evaluated were improved during the course of this study in 33 cats with stress-related signs. The behaviour of most of the cats improved after 15 or 30 days of L-theanine administration, leading to high owner satisfaction. Zylkene comes in capsule form. This is ideal for hiding in your dog’s food, or alternatively, owners can break it open and sprinkle the powder directly into food – much easier than a tablet if you have a cat! Amat M, Camps T, Manteca X. Stress in owned cats: behavioural changes and welfare implications. J Feline Med Surg. 2016;18(8):577–86. Yoto A, Motoki M, Murao S, Yokogoshi H. Effects of L-theanine or caffeine intake on changes in blood pressure under physical and psychological stresses. J Physiol Anthropol. 2012;31:28.

Pryor PA, Hart BL, Bain MJ, Cliff KD. Causes of urine marking in cats and effects of environmental management on frequency of marking. J Am Vet Med Assoc. 2001;219(12):1709–13. faq_q1: Hvilken type Anxitane™ passer til mit kæledyr? faq_a1: • Anxitane™ S anvendes til katte og små hunde under 10 kgKern L. La transmission de la peur. In: Beata C, ed. La Communication. Collection Zoopsychiatrie. Marseille, France: Solal Editeurs; 2005:191–196. Horwitz DF. Behavioral and environmental factors associated with elimination behavior problems in cats: a retrospective study. Appl Anim Behav Sci. 1997;52(1):129–37. Here are some of the best calming products for dogs and cats. Natural ingredient based calming supplements 1) Zylkene Yokogoshi H, Kobayashi M. Hypotensive effect of γ-glutamylethylamide in spontaneously hypertensive rats. Life Sci. 1998;62:1065–8. Ideally Anxitane should be given 2 weeks before the stressful event but effects are often seen a lot sooner