Oil derived from sesame is rich in linoleic and oleic acids, the majority of which are gamma-tocopherol and other isomers of vitamin E. Some of the specific amino acids found in each serving include lysine, tryptophan and methionine.

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Sesame seeds can be consumed as is or made into tahini or sesame oil as a nutritious and delicious dietary addition. Moazzami, A. A., Andersson, R. E., and Kamal-Eldin, A. HPLC analysis of sesaminol glucosides in sesame seeds. J Agric Food Chem 2006;54(3):633-638. View abstract. Similarly, a 2012 study published in the Journal of Nutrition also found that dietary lignans may act as a natural cancer treatment to reduce breast cancer risk by modifying tumor characteristics. In the study, lignan intakes were associated with a lower risk of estrogen receptor negative breast cancer. Caminiti, L., Vita, D., Passalacqua, G., Arrigo, T., Barberi, S., Lombardo, F., and Pajno, G. B. Tahini, a little known sesame-containing food, as an unexpected cause of severe allergic reaction. J Investig Allergol Clin Immunol 2006;16(5):308-310. View abstract. Sesame fruit is actually a “capsule” that is rectangular and two to eight centimeters long. The fruit naturally splits open and releases the seeds when it’s mature.A 2005 in vitro study conducted by the Department of Nutritional Sciences at the University of Toronto investigated the effects of giving 25 grams of unground whole flaxseeds and sesame seeds to healthy postmenopausal women over a four-week period. Urine test results showed an increase in mammalian lignans from the women receiving both whole flaxseeds and sesame seeds, suggesting that both are effectively converted by the bacterial flora in the colon, potentially helping protect against the growth and spread of colon cancer cells. Kamal-Eldin, A., Frank, J., Razdan, A., Tengblad, S., Basu, S., and Vessby, B. Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats. Lipids 2000;35(4):427-435. View abstract. Chen, P. R., Tsai, C. E., Chang, H., Liu, T. L., and Lee, C. C. Sesamol induces nitric oxide release from human umbilical vein endothelial cells. Lipids 2005;40(9):955-961. View abstract.

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Tsai, H. J., Kumar, R., Pongracic, J., Liu, X., Story, R., Yu, Y., Caruso, D., Costello, J., Schroeder, A., Fang, Y., Demirtas, H., Meyer, K. E., O'Gorman, M. R., and Wang, X. Familial aggregation of food allergy and sensitization to food allergens: a family-based study. Clin Exp Allergy 2009;39(1):101-109. View abstract. el Tahir, K. E., Hamad, E. A., Ageel, A. M., Abu Nasif, M. A., and Gadkarim, E. A. Effects of sesame and cod liver oils on prostacyclin synthesis by the rat thoracic aorta. Arch Int Pharmacodyn Ther 1988;292:182-188. View abstract. Hou, R. C., Huang, H. M., Tzen, J. T., and Jeng, K. C. Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells. J Neurosci Res 2003;74(1):123-133. View abstract. Pastorello, E. A., Varin, E., Farioli, L., Pravettoni, V., Ortolani, C., Trambaioli, C., Fortunato, D., Giuffrida, M. G., Rivolta, F., Robino, A., Calamari, A. M., Lacava, L., and Conti, A. The major allergen of sesame seeds (Sesamum indicum) is a 2S albumin. J Chromatogr B Biomed Sci Appl 2001;756(1-2):85-93. View abstract. Sesame oil might lower blood sugar levels. Taking sesame oil along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.Chavali, S. R., Zhong, W. W., and Forse, R. A. Dietary alpha-linolenic acid increases TNF-alpha, and decreases IL-6, IL-10 in response to LPS: effects of sesamin on the delta-5 desaturation of omega6 and omega3 fatty acids in mice. Prostaglandins Leukot Essent Fatty Acids 1998;58(3):185-191. View abstract. Beyer, K., Grishina, G., Bardina, L., and Sampson, H. A. Identification of 2 new sesame seed allergens: Ses i 6 and Ses i 7. J Allergy Clin Immunol 2007;119(6):1554-1556. View abstract. Furumoto, T., Takeuchi, A., and Fukui, H. Anthrasesamones D and E from Sesamum indicum roots. Biosci Biotechnol Biochem 2006;70(7):1784-1785. View abstract.

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Fujiyama-Fujiwara, Y., Umeda-Sawada, R., Kuzuyama, M., and Igarashi, O. Effects of sesamin on the fatty acid composition of the liver of rats fed N-6 and N-3 fatty acid-rich diet. J Nutr Sci Vitaminol (Tokyo) 1995;41(2):217-225. View abstract. Xu, H., Yang, X., Yang, J., Qi, W., Liu, C., and Yang, Y. [Antitumor effect of alcohol extract from Sesamum indicum flower on S180 and H22 experimental tumor]. Zhong Yao Cai 2003;26(4):272-273. View abstract. Navuluri, L., Parvataneni, S., Hassan, H., Birmingham, N. P., Kelly, C., and Gangur, V. Allergic and anaphylactic response to sesame seeds in mice: identification of Ses i 3 and basic subunit of 11s globulins as allergens. Int Arch Allergy Immunol 2006;140(3):270-276. View abstract.

Sesame plants are highly tolerant to droughts, durable and grow where many other crops may fail, which is why they have been a staple plant for so many years in deserts and barren areas. Ashakumary, L., Rouyer, I., Takahashi, Y., Ide, T., Fukuda, N., Aoyama, T., Hashimoto, T., Mizugaki, M., and Sugano, M. Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism 1999;48(10):1303-1313. View abstract. James, C., Williams-Akita, A., Rao, Y. A., Chiarmonte, L. T., and Scheider, A. T. Sesame seed anaphylaxis. N Y State J Med 1991;91(10):457-458. View abstract. Mosayebi, G., Ghazavi, A., Salehi, H., Payani, M. A., and Khazae, M. R. Effect of sesame oil on the inhibition of experimental autoimmune encephalomyelitis in C57BL/6 mice. Pak J Biol Sci 2007;10(11):1790-1796. View abstract.

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Takatsuki, S., Nemoto, S., Sasaki, K., and Maitani, T. Determination of acrylamide in processed foods by LC/MS using column switching. Shokuhin Eiseigaku Zasshi 2003;44(2):89-95. View abstract. Phillips, K. M., Ruggio, D. M., and Ashraf-Khorassani, M. Phytosterol composition of nuts and seeds commonly consumed in the United States. J Agric Food Chem 2005;53(24):9436-9445. View abstract. For best results, try rotating between all four in your diet to take advantage of the multitude of health benefits that each has to offer. Sesame Seeds vs. Sesame Oil vs. Tahini Unfortunately, it appears more and more people have developed sesame allergies in recent years, leading to the U.S. Food and Drug Administration to label it the ninth major food allergen in the U.S. at the start of 2023. That, of course, doesn’t take away from the incredible health benefits of sesame seeds, but it does mean a good number of people should avoid them.Williamson, K. S., Morris, J. B., Pye, Q. N., Kamat, C. D., and Hensley, K. A survey of sesamin and composition of tocopherol variability from seeds of eleven diverse sesame (Sesamum indicum L.) genotypes using HPLC-PAD-ECD. Phytochem Anal 2008;19(4):311-322. View abstract. Sesame seeds are derived from the sesame plant, which produces small pods that burst open upon reaching maturity to reveal the nutritious seed. Tahini, also sometimes called tahina, is a type of sesame seed paste that is made by grinding sesame seeds. Taking advantage of the tahini nutrition profile by adding a few servings to your diet is a tasty and convenient way to increase your intake of sesame seeds and enjoy the numerous nutrients contained in every bite. Sesame seeds are truly one of the most ancient foods on Earth. In fact, sesame plants are the oldest known plant species to be grown primarily for their seeds and oils rather than for their leaves, fruits or vegetables.