Culminating the story arc extending from 61 Hours, Reacher makes it to his destination in northeastern Virginia: the headquarters of his old unit, the 110th MP. On arriving though, Reacher finds out that the new commanding officer, Major Susan Turner, has been arrested. Soon he too finds himself taken into custody, pending the trial of two crimes he allegedly committed while he was in the army. Reacher and Turner set out on a journey; Turner in hopes of clearing her name and Reacher to prove the charges fraudulent or if true then atone for them.

The settings for many of the novels are found within the United States of America, in locales ranging from major metropolitan areas like New York City, Los Angeles and Washington, D.C., to small rural towns in the Midwestern United States and Southern United States. Reacher's travels outside the United States have taken him to rural England ( The Hard Way, Maybe They Have a Tradition), London ( Personal), Hamburg ( Night School) and Paris ( The Enemy, Personal). And he's about to find a big one, on a deserted Arizona road, where a Jeep has crashed into the only tree for miles around. Under the merciless desert sun, nothing is as it seems. Baldacci, David, ed. (2014). FaceOff. New York, New York: Simon and Schuster. ISBN 9781476762074 . Retrieved 31 December 2016. A contemporary version of the knight in shining armour . . . Reacher is a mythic figure.' Literary Review

When someone makes a small anonymous deposit into Reacher's bank account, it triggers his fixation for math and his investigative instincts. Reacher deduces that the deposit is a signal only the eight former members of his elite team of army investigators would use. Obsessed with math like Reacher, Frances Neagley locates him because of the brutal death of one of their own. They race to reunite with the survivors of their old team and raise the living, bury the dead, and connect the dots in a mystery that grows more complex with more murders. With the lives of those Reacher considers family at stake, his usual emotionless demeanor breaks and he says of the killers, "They are dead men walking." The team falls into their old roles and routines with ease, their motto still their sacred rule: You do not mess with the Special Investigators. Reacher hitches a ride in Texas. Carmen, the driver, is a mother of a young girl and is trapped in an abusive marriage. She requests Reacher's help. After some deliberation Reacher consents. However, at her remote ranch in Echo County Reacher encounters lies, prejudice and hatred climaxing in Carmen being arrested for the murder of her husband. With Carmen's true motives cast into doubt, Reacher finds himself investigating the truth.

Just as Reacher helps Holly Johnson, an attractive young woman struggling with her crutches on a Chicago street, they are both kidnapped at gunpoint. Reacher and the woman are thrown into a dark van and taken 2,000 miles across America, completely unaware why they were kidnapped and where they are going. Finding themselves trapped in a seemingly remote place, they must work together to find the answers. Reacher makes a stop in an agrarian town called Mother's Rest. There a woman, Michelle Chang, enlists his help to find a missing colleague. Reacher goes where he wants, when he wants. That morning he was heading west, walking under the merciless desert sun—until he comes upon a curious scene. A Jeep has crashed into the only tree for miles around. A woman is slumped over the wheel. Hemingway also makes a call to the New York Police Department about the Son of Sam based on the description given to her by Reacher. They then go to a motel where Jill dies of a myocardial infarction. [9] Reacher leaves the motel after informing the police of her death.

This novel was adapted for the first season of the 2022 series, Reacher starring Alan Ritchson in the titular role.