Aktywność biologiczna korzenia lukrecji wynika z bogatego składu chemicznego, przede wszystkim z obecności saponin triterpenowych (głównie glicyryzynyoraz solikwasu glicyryzynowego), flawonoidów(np. glabrydyny i pochodnych izoflawonu), kumaryn. Geng-He Chang i wsp.: Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. J Ethnopharmacol, 2021, 275, 114116.

Parvin Zulfugarova i wsp.: A mechanistic review of pharmacological activities of homeopathic medicine licorice against neural diseases. Front Neurosci, 2023, 17, 1148258. After Alfonso’s death, Borgia's father arranged for her to be married to Alfonso d'Este, Duke of Ferrara, in early 1502. Borgia's new husband was initially hesitant because of the Borgia reputation. The couple soon moved out of Rome to Ferrara, escaping the endless scheming of her father and brother, and the pair had several children (many of whom died young). With this marriage, Borgia managed to rise above her family’s reputation, and she thrived in her new surroundings. Later Years Lukrecja działa pozytywnie na układ oddechowy, ponieważ może zmniejszać przewlekły kaszel i redukuje objawy alergicznego nieżytu nosa.Lucrezia had become very weak during the pregnancy and fell seriously ill after the birth. After seeming to recover for two days, she worsened again and died on 24 June the same year. She was buried in the convent of Corpus Domini. [26] Appearance [ edit ] Portrait of a Woman by Bartolomeo Veneto, traditionally presumed to be Lucrezia Borgia. Signature of Lucrezia Borgia in a letter to her sister-in-law Isabella Gonzaga, March 1519 Tomb of Alfonso I d'Este and Lucrezia Borgia, Ferrara Ann M Bode i wsp.: Chemopreventive Effects of Licorice and Its Components. Curr Pharmacol Rep, 2015;1(1):60-71., 1(1), 60-71. Anyone else who spots something suspicious can always report it to our Customer Service team, so our Fraud team can investigate.

Glabridin is a chemical compound that is found in the root extract of licorice ( Glycyrrhiza glabra). Her family arranged several marriages for her that advanced their own political position including Giovanni Sforza, Lord of Pesaro and Gradara, Count of Cotignola; Alfonso of Aragon, Duke of Bisceglie and Prince of Salerno; and Alfonso I d'Este, Duke of Ferrara. Alfonso of Aragon was an illegitimate son of the King of Naples and tradition has it that Lucrezia's brother Cesare Borgia may have had him murdered after his political value waned. Jiyun Ahn i wsp.: Anti-obesity effects of glabridin-rich supercritical carbon dioxide extract of licorice in high-fat-fed obese mice. Food Chem Toxicol, 2013, 51, 439-45. Dechao Tan i wsp.: Glycyrrhizic Acid and Its Derivatives: Promising Candidates for the Management of Type 2 Diabetes Mellitus and Its Complications. Int J Mol Sci, 2022, 23(19), 10988. W prestiżowym magazynie The Lancet opublikowano w 2003 r. badania dotyczące powiązania działania pozyskiwanej z korzenia lukrecji glicyryzyny z koronawirusem.a b Pietro Bembo: A Renaissance Courtier Who Had His Cake and Ate It Too, Ed Quattrocchi, Caxtonian: Journal of the Caxton Club of Chicago, Volume XIII, No. 10, October 2005. Thrower, Stephen (1999). Beyond terror: the films of Lucio Fulci. FAB Press. p.291. ISBN 9780952926054. Borgia was married for the first time before entering her teenage years. She was engaged to one nobleman and then another before her father had the engagements dissolved so that he could arrange for her to be married to Giovanni Sforza, 15 years her senior, who was Lord of Pesaro and Count of Catignola. Borgia’s father, Cardinal Rodrigo Borgia, was named Pope Alexander VI in 1492, and Borgia was married a year later. They were married in 1498, making Lucrezia the Duchess consort of Bisceglie and Princess consort of Salerno. Lucrezia – not her husband – was appointed governor of Spoleto in 1499; Alfonso fled Rome shortly afterwards but returned at Lucrezia's request, only to be murdered in 1500. [11] On 26 February 1491, a matrimonial arrangement was drawn up between Lucrezia and the Lord of Val D'Ayora, in the kingdom of Valencia, Don Cherubino Joan de Centelles, which was annulled less than two months later in favour of a new contract engaging Lucrezia to Don Gaspare Aversa, count of Procida. [4] When Rodrigo became Pope Alexander VI, he sought to be allied with powerful princely families and founding dynasties of Italy. He therefore called off Lucrezia's previous engagements and arranged for her to marry Giovanni Sforza, a member of the House of Sforza who was Lord of Pesaro and titled Count of Catignola. [5] Giovanni was an illegitimate son of Costanzo I Sforza and a Sforza of the second rank. He married Lucrezia on 12 June 1493 in Rome. [3]

Chrzanowski, J., Chrzanowska, A., & Graboń, W. (2020). Glycyrrhizin: An old weapon against a novel coronavirus.Phytotherapy Research. Borgia was born during the Italian Renaissance, when artists, architects, and scientists were reaching new levels of accomplishment and transforming their world. While famous figures such as Leonardo da Vinci were innovating their way into history, the Borgia legacy, conversely, is one of violent political corruption involving a power-hungry clan who sought to control large parts of Italy. MarriagesLucrezia met the famed French soldier, the Chevalier Bayard while the latter was co-commanding the French allied garrison of Ferrara in 1510. According to his biographer, the Chevalier became a great admirer of Lucrezia's, considering her a "pearl on this Earth". [25] Lukrecja znana jest również z łagodzenia dolegliwości trawiennych, objawów menopauzy i zmian skórnych spowodowanych np. trądzikiem. There has been speculation that during the prolonged process of the annulment, Lucrezia consummated a relationship with someone, perhaps Alexander's chamberlain Pedro Calderon, also named Perotto. [9] In any case, families hostile to the Borgias would later accuse her of being pregnant at the time her marriage was annulled for non-consummation. She is known to have retired to the convent of San Sisto in June 1497 to await the outcome of the annulment proceedings, which were finalized in December of the same year. The bodies of Pedro Calderon [9] and a maid, Pantasilea, were found in the Tiber in February 1498. In March 1498, the Ferrarese ambassador claimed that Lucrezia had given birth, but this was denied by other sources. A child was born, however, in the Borgia household the year before Lucrezia's marriage to Alfonso of Aragon. He was named Giovanni but is known to historians as the " Infans Romanus". H H. Sasaki H H. i inni, Effect of glycyrrhizin, an active component of licorice roots, on HIV replication in cultures of peripheral blood mononuclear cells from HIV-seropositive patients., „Pathobiology”, 70 (4), 2002–2003, s.229-236, DOI: 10.1159/000069334, PMID: 12679601 .