Frequency not known. As the listed undesirable effects are based on spontaneous reports, assigning accurate frequency of occurrence for each is not possible. The strengths of this study include the large sample size and the fact that it provides real-world experience of Canesten product use. Real-world data relate to the routine use of a product/intervention within the context of a self-care setting; hence, the data generated differ from, and complement, those provided under the well-controlled conditions of a randomized trial. Real-world data provide important patient insights on how a product works in a real-life setting, reflecting actual use in practice and free from the specific limitations of a randomized trial. In this way, such data bridge the efficacy/effectiveness gap between how a product performs in a randomized trial versus its performance in a real-life setting. To date, the only similar real-world study published in this disease area has been a prospective study, conducted in Germany, examining the efficacy and tolerability of Canesten products in women with vulvovaginal mycoses being treated by a gynecologist. 22 In the current real-world data study, consumers opted to take (and bought) Canesten products themselves (no third-party intervention or prescription was involved/required), so the self-reported results may be considered as neutral and unbiased. This is the first retrospective real-world data study to examine experience with a wide range of OTC Canesten products in women who have experienced thrush/vaginal yeast infection and, as such, provides consumer-important information that adds supplementary value to data obtained from randomized trials. Randomized trials aim to examine the effect of thrush/vaginal yeast infection therapies on outcomes, such as clinical cure rate (i.e. complete resolution of symptoms of thrush/vaginal yeast infection) and/or mycological cure rate (a negative Candida culture). 3, 10 The findings of the questionnaire used in this study, however, reveal not only that administration of a Canesten product improves symptoms of thrush/vaginal yeast infection in over 90% of users but also highlights the rapid speed of onset of Canesten products for the symptomatic relief of thrush/vaginal yeast infection, with 42% of consumers perceiving an improvement in associated symptoms within 4h, and over 75% reporting relief of symptoms within 1day after taking a Canesten product. Put a strip of cream onto your fingertip. A 1cm strip is enough to treat an area the size of the hand. Apply it in a thin layer to the affected area and rub it in gently. Canesten Thrush Combi Soft Gel Pessary is the complete treatment for vaginal thrush due to its treatment of both internal and external symptoms. Canesten Thrush Combi Soft Gel Pessary & External Cream

Your personal data will be retained indefinitely on our secure servers, as required by regulation regarding healthcare provision. Almost all ( n=465, 98%) respondents reported that their thrush/vaginal yeast infection impaired their daily life to some extent before starting treatment, with only 10 (2%) reporting that their symptoms had no impact. Data availability: Data generated and analyzed during the current study are available from the corresponding author on reasonable request. You have the right to rectify or correct any personal data we hold for you if it is inaccurate or incomplete. The applicator should be used to insert the pessary as high as possible into the vagina, preferably before going to sleep at night for convenient and comfortable treatment.

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Do this 2 or 3 times a day for at least 2 weeks. The cream will work better if you can use it 3 times a day. How to use pessaries Some special precautions you should consider when using Canesten Thrush Combi Soft Gel Pessary 500mg & 2 Cream: When used in pregnancy, the soft gel pessary should be inserted without using an applicator (see “Pregnancy”).Therapies recommended in current global guidelines for the management of women with thrush/vaginal yeast infection include topical/intra-vaginal (e.g. clotrimazole) or oral azoles (e.g. fluconazole). 6 – 9 Clotrimazole has long been used for the treatment of women with thrush/vaginal yeast infection – its use is supported by a wide evidence base. 10 – 14 Likewise, fluconazole has been shown to be effective in the treatment of women with thrush/vaginal yeast infection. 3

Such requests shall be free of charge save where the request is manifestly unfounded or excessive, including (but not limited to) if the request is repetitive or complying with requests for further copies of the same information previously provided by us. In such circumstances, we reserve the right to charge you a reasonable fee in dealing with such requests, or alternatively, we may refuse to comply with your request in these circumstances. You should not use Canesten Thrush Soft Gel Pessary & Cream Combi if you are allergic to any of the ingredients listed in the patient information leaflet and it should not be used to treat nail or scalp fungal infections. Canesten Thrush Soft Gel Pessary 500mg Pessaries need moisture in the vagina to dissolve completely. If they do not dissolve, pieces of the pessary may crumble and fall out of the vagina. You may notice this if you have vaginal dryness. If symptoms of thrush do not resolve within 7 days of taking treatment women should see their GP. HOW DO YOU TAKE CANESTEN 500MG SOFT GEL PESSARY TO TREAT VAGINAL THRUSH? A foul smelling discharge from the vagina. This is because Canesten Thrush Soft Gel Pessary may not be the right treatment for you.

Canesten Thrush Combi Soft Gel Pessary & External Cream

Below is a list of Canesten Thrush Soft Gel Pessary 500mg Side Effects experienced more, or less when people have used Canesten Thrush Soft Gel Pessary 500mg. For a full list, please refer to the patient information leaflet. Among women using a single product treatment containing thrush internal cream, 116 of 123 (94%) using Canesten Thrush Pessary/Canesten Vaginal Tablet and 38/41 (93%) using Canesten Thrush Soft Gel Pessary (available in the United Kingdom only) reported itching and burning relief within 3days of application. Among UK women using Canesten Thrush Internal Cream, 75 of 87 (86%) reported itching and burning relief up to and after 1day of application. If you’re using the external cream and you forget to put it on, use it as soon as possible and continue putting it on 2 to 3 times a day as usual. The following side effects are signs of an allergic reaction, immediately stop using this medication and seek medical aid:

The other ingredients are benzyl alcohol, polysorbate 60, sorbitan stearate, cetyl palmitate, cetostearyl alcohol, octyldodecanol and purified water. Among 84 respondents who had used products other than Canesten to treat a thrush/vaginal yeast infection episode, 48 (58%) stated that a Canesten product relieved their symptoms faster than these other products, 18 (21%) reported no difference, and 18 (21%) could not answer the question. Vaginal thrush is a yeast infection which almost all women experience at some time in their lives. It happens when the natural balance in your vagina is disturbed, meaning the natural yeast or fungus in your vagina can grow and cause infection. This is what leads to thrush.

Uses / Instructions

Ethical approval: According to the ‘Governance arrangements for research ethics committees:2020 edition’ document published by the NHS Health Resource Authority, UK, Section 2.3.15 (linked here), ‘Market research may be undertaken by professional market researchers, for example, for public health research or on behalf of pharmaceutical or medical device companies. Where such research is conducted by professional market researchers in accordance with the principles set out in the Market Research Society Code of Conduct or with the Legal and Ethical Guidelines issued by the British Healthcare Business Intelligence Association (BHBIA), it does not require REC review, except where otherwise required by law, for example, if it requires approval under the Mental Capacity Acts’. In line with BHBIA guidelines, in this study, participants were informed about the objective and use of the study prior to completing the questionnaire. As this study involved no randomization of participants, no intervention, no provision of the product to the consumers by Bayer or IQVIA, and no healthcare professional input or consultation of medical records, ethical approval or regulatory submission was not required.