The dried aqueous extract of standardised red vine leaves (AS 195) is a food supplement available in capsules. Red vine leaf extract has been available in France for the treatment of symptoms associated with venous insufficiency. In the UK it is sold as a dietary supplement for the maintenance of healthy leg-vein circulation, in particular to avoid tired, heavy and aching legs that result from long periods of standing or sitting. Recent studies have investigated the action of flavonoids in preventing atherosclerotic plaques (Hollman and Katan, 1997). Bioflavonoids or flavonoids are a class of water-soluble substances found in a number of plants or plant-derived products. It is believed that flavonoids have a wide range of beneficial effects when taken in the diet, including anti-inflammatory, antihistaminic and antiviral action. Formica and Regelson (1995) concluded that flavonoids are important in the maintenance of capillary wall integrity and resistance. The LipoTherapeia® treatment, a combination of deep-acting, high-power radiofrequency and deep acting, high-power ultrasound cavitation, is currently the strongest SAFE skin tightening, non-surgical bum lifting and cellulite treatment in London

Kalus et al’s (2004) study was designed to identify the improvement of cutaneous microcirculation and oxygen supply. This double-blind randomised placebo-control crossover trial involved 71 patients with cutaneous microcirculation. Group one (n=36) received red vine leaf extract AS 195 360mg daily for six weeks followed by a four-week washout (break between treatments) and six-week placebo treatment. Group two (n=35) received placebo, then washout, then red vine leaf extract AS 195 360mg daily for six weeks. After six weeks of treatment, the intervention group had an increase in microvascular bloodflow values compared with a decrease in the placebo group. Transcutaneous oxygen increased in the intervention group, while in the placebo group it decreased. Leg circumference decreased in the intervention group compared with the placebo group. Evaluating the evidence

What are the characteristics of the Red Vine?

To begin with, as with all products and treatments, make sure you consult your doctor before embarking on the treatment. The doctor will use their knowledge of medicine and your body to determine whether you may be allergic to the product and also to assess whether the product is good for your body or not. Hollman, P.C., Katan, M.B. (1997) Absorption, metabolism and health effects of dietary flavonoids in man. Biomedical Pharmacotherapy; 51: 8, 305-310. Our red vine leaves are harvested when its nutrient content is at its highest; the leaves are then dried and its nutrients extracted using precise temperature controls and purified water, guaranteeing a grapevine extract of the highest quality. Each tablet contains 360mg of natural red vine leaf extract - equivalent to 5,400mg of fresh red vine leaf - including 40% polyphenols, the key ingredient. Take daily for at least six weeks to start seeing the full benefits. Chat-GPT and similar tools copy the web to regurgutate meaningless lowest common denominator platitudes, i.e. generally accepted myths that often have nothing to do with reality. Plus plenty of inaccuracies, misinformation and a healthy added dose of literally made up stuff - what AI experts call “AI hallucinations”. There is little research on the nutritional properties of vine leaves. Some studies say they contain good amounts of vitamin C, others that they are a moderate source of calcium or magnesium. Some say they contain healthy Omega-3 fatty acids. However, more research is needed to confirm these facts.

An earlier (2002) study under the leadership of Dr Stephan Nees found that treating cells damaged by CVI with AS 195 led to the restoration of cell functionality, showing that red vine leaf extract is, at least to a certain extent, able to reverse existing damage in the veins.

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In contrast, in France, Germany and Italy these natural extracts have been widely researched and used for decades, either as nutritional supplements or even actual medicines and are very popular with women suffering from CVI, water retention and cellulite. This means that the person no longer suffers from the pain that comes with the conditions. It also minimized the pain and tingling sensations in the legs. As a result of this the person’s mobility is made easier as there is little to no pain, swelling, or stiffness in the legs. Common symptoms include fat accumulation, oedema (water retention), heavy legs, muscle cramps, pain, varicose veins and cellulite.

The effects such as tired legs were also remarkably improved as a result of using red vine leaf extracts. The product was therefore shown to be effective even when used for a short while. Red Vine Leaf Extract Benefits In terms of safety and tolerance, red vine leaf extract proved good or satisfactory, which was expected from a flavonoid-rich natural product. Natural remedies for heavy, tired legs, water retention and cellulite Of course, the aesthetics industry is already full of myths, inaccuracies, platitudes and hallucinations anyway, so the advent of AI does not make much of a difference. The beauty industry has always been full of BS, AI or no AI.The effects of venous hypertension include deposition of haemosiderin (iron deposits) and fibrin in the perivessel tissues, along with subtle changes in skin texture that can eventually lead, if untreated, to trophic skin changes and varicose leg ulcers. Management of venous hypertension The phytonutrients present in its leaves act as natural venotonics, angioprotectors and anti-edematous. In other words, they contribute to the tonicity and protection of blood vessels and capillaries. They are particularly capable of reducing the permeability of blood vessels and improving their resistance. Therefore, a red vine treatment may be of interest to combat venous insufficiency, to alleviate the sensation of heavy and / or swollen legs, among other benefits.

One of the first studies to assess the effectiveness of red vine leaf extracts (Antistax) asked 71 people with leg swelling (due to chronic venous insufficiency) to take 360mg red vine leaf extracts, or placebo during two separate periods of 6 weeks. This meant that each person tried both treatments and acted as their own controls. The leaves have the same resveratrol properties as the wine, but in addition to this they have a vast array of other health properties, including protective polyphenols and anthocyanins. In recent studies it has been proven to be an effective remedy for the effects that come as a result of CVI and varicose veins. This is what makes it a useful bath for the legs, especially for someone that spends their whole day on their feet. Holland & Barrett Leg Vein Formula is carefully developed to help maintain healthy circulation in the legs. The capsules contain Red Vine leaf extract which contributes to good blood flow in the legs, along with grapeseed extract and Vitamin C. The placebo group demonstrated an increase in lower leg volume at six weeks and at 12 weeks. Patients treated with red vine leaf extract AS 195 showed a decrease in mean volume compared with the control group. The results of changes in ankle circumference were similarly positive, with reductions in the active treatment groups but little change in the placebo group. All patients in the active treatment groups had subjective improvements in symptoms at six weeks, and the changes were significantly greater after 12 weeks.However, this doesn’t mean vine leaves aren’t healthy. There is ample research on the properties and health benefits of red vine leaves and several uses have been identified: The leaves of the grape vine (Vitis vinifera) are an increasingly popular culinary vegetable, used in a variety of recipes from cuisines around the world. But more important, vine leaves are an excellent source of powerful antioxidant compounds with impressive health effects. The red vine leaf, in particular, has been found to help improve conditions related to poor blood circulation, notably varicose veins and associated symptoms.