The town of Ajisu separated from Yamaguchi on November 23, 1947, followed by the town of Ogōri on November 1, 1949. Yamaguchi annexed the town of Ōuchi on May 1, 1963 and the village of Suzenji on November 3, 1963. On October 1, 2005 Yamaguchi merged with town of Tokuji (from Saba District), and the towns of Aio, Ajisu and Ogōri (all from Yoshiki District);. Yoshiki District was dissolved as a result of this merger. On January 16, 2010 Yamaguchi absorbed the town of Atō (from Abu District). Yoshiyuki Sadamoto, a Japanese character designer, manga artist, and one of the founding members of the Gainax anime studio [11] Baer C, Claus R, Plass C . Genome-wide epigenetic regulation of miRNAs in cancer. Cancer Res 2013; 73: 473–477. Kastl L, Brown I, Schofield AC . miRNA-34a is associated with docetaxel resistance in human breast cancer cells. Breast Cancer Res Treat 2012; 131: 445–454.

Yet unlike so many victims of radiation exposure, Yamaguchi slowly recovered and went on to live a relatively normal life. He served as a translator for the U.S. armed forces during their occupation of Japan, and later taught school before resuming his engineering career at Mitsubishi. He and his wife even had two more children in the 1950s, both of them girls. Yamaguchi dealt with the horrific memories of Hiroshima and Nagasaki by writing poetry, but he avoided discussing his experiences publicly until the 2000s, when he released a memoir and became part of the anti-atomic weapons movement. He later journeyed to New York in 2006 and spoke about nuclear disarmament before the United Nations. “Having experienced atomic bombings twice and survived, it is my destiny to talk about it,”he said in his speech.He is seen with Kageyama, Tsukishima, and Tanaka intimidating Yahaba and Kindaichi upon their arrival to Aoba Johsai and hearing the two talking about the team. He does not play in the match but shows support from the sidelines. He would become fearful when Tōru Oikawa arrived to the match and began aiming his serves at Tsukishima. Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D et al. MicroRNA-34a is tumor suppressive in brain tumors and glioma stem cells. Cell Cycle 2010; 15: 1031–1036.

Yamaguchi is a pretty shy person who relies on others early on, most likely stemmed from being bullied because of his appearance. Despite this, Yamaguchi is generally a nice person but does tend to join Tsukishima in teasing others, mainly Kageyama and Hinata. He does show that he is a loyal friend and a supportive teammate. Yamaguchi can at times be seen defending Tsukishima from things he believes were insults toward his friend.

Sterngold, James (January 22, 1995). "QUAKE IN JAPAN: GANGSTERS; Gang in Kobe Organizes Aid for People In Quake"– via NYTimes.com. When Taoka inherited the title of kumichō, it was merely a local family with only a few dozen members. It was Taoka who made Yamaguchi-gumi Japan's largest criminal organization. He urged his underlings to have legitimate businesses and allowed them to have their own families, which became quasi– subsidiary families of Yamaguchi-gumi. He also created a structural system in the family. Wakagashira were elected as underbosses to the kumichō and some powerful members were elected as wakagashira-hosa (deputy underbosses). [ citation needed] PCa is the most frequent tumor and the second leading cause of cancer-related death in the United States. 56 Similar to breast cancer, the observation suggesting a direct role for miR-34a in PCa is its silence by aberrant CpG methylation of its promoter, and downregulation of miR-34a has been observed in prostate tumors compared with normal tissues. 11 The expression levels varied depending on the methodologies used for expression and controls. 57, 58, 59 There are contradictory findings regarding the increased levels of miR-34a achieved in PCa samples compared with benign counterparts, 60 which remains to be elucidated by more extensive studies. Indeed, a major limitation of these studies is the relatively small sample. Hence, it is unclear whether miR-34a has an oncogenic role in PCa. As malignancy is a heterogeneous disease, the role of miR-34a needs to be further examined in the specific subtypes of PCa.

Prime Minister Shinzō Abe represented first Yamaguchi's 1st then 4th district in the House of Representatives; his father Shintaro also represented Yamaguchi. Adachi N, Lieber MR . Bidirectional gene organization: a common architectural feature of the human genome. Cell 2002; 109: 807–809.

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Lodygin D, Tarasov V, Epanchintsev A, Berking C, Knyazeva T, Körner H et al. Inactivation of miR34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 2008; 7: 2591–2600. By his third-year of high school, Yamaguchi is shown to have cut his hair to a shorter length. He kept this look after the timeskip. Although he does not play in this match, he is shown to narrowly miss being hit by one of Hyakuzawa's spikes during the warm-ups, which leaves him being fearful. After the preliminaries, Yamaguchi is seen continuing to work on his serve and finally managing to perform a float serve that Nishinoya is unable to receive. Kato M, Paranjape T, Ullrich R, Nallur S, Gillespie E, Keane K et al. The MiR-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells. Oncogene 2009; 28: 2419–2424. MicroRNAs (miRNAs) are short 18–24 nt RNA that inhibit the transcription or translation of mRNA ( 16 – 20). MiRNA regulation of gene expression plays a role in development, differentiation, proliferation, and apoptosis ( 21 – 26). Expression of miRNAs are abnormal in a variety of cancers, and miRNA may play a role in tumorigenesis ( 27 – 34). Several miRNA have been identified that may act as tumor suppressor genes ( 35 – 40).