Patients should consult a doctor or pharmacist if symptoms persist for more than 3 days, or worsen.

Lemsip Max Cold and Flu Capsules - Summary of Product Lemsip Max Cold and Flu Capsules - Summary of Product

Use during breastfeeding should be avoided, unless recommended by a healthcare professional (see section 4.6). Do not take if: allergic to any ingredient, if you have heart disease, high blood pressure, overactive thyroid, or are taking or have taken MAOI's (antidepressants) within 14 days, if you are taking other sympathomimetic decongestants. Sympathomimetic agents: Concomitant use of phenylephrine with other sympathomimetic amines can increase the risk of hypertension and other cardiovascular side effects (see section 4.3).CYP Inhibitors: Caffeine undergoes extensive metabolism by hepatic microsomal cytochrome P450, factors known to alter the activity of this enzyme system may influence caffeine clearance. Thus, caffeine elimination is enhanced in cigarette smokers and inhibited by cimetidine, disulfiram, and oral contraceptive steroids. The product should be avoided during lactation unless recommended by a healthcare professional. There are limited data on the use of phenylephrine in lactation. The most commonly reported adverse events following dosing with caffeine are GI irritation and CNS stimulation. Antiemetics: The speed of absorption of paracetamol may be increased by metoclopramide or domperidone and absorption reduced by cholestyramine.

Lemsip Max Day and Night Cold and Flu Relief Capsules - Boots

Hypersensitivity to paracetamol, phenylephrine, caffeine or to any of the excipients listed in section 6.1. Taken during pregnancy it appears that the half-life of caffeine is prolonged. This is a possible contributing factor in hyperemesis gravidarum.

Due to the presence of caffeine, the product should be taken with care in patients with a history of peptic ulcers.

Lemsip | Superdrug Lemsip | Superdrug

Symptoms - emesis and convulsions may occur. No specific antidote. However, treatment is usually fluid therapy. Fatal poisoning is rare. If symptoms become apparent or overdose is suspected, consult a doctor immediately. Paracetamol: Paracetamol is absorbed rapidly and completely mainly from the small intestine, producing peak plasma levels after 15-20 minutes following oral dosing. The systemic availability is subject to first-pass metabolism and varies with dose between 70% and 90%. The drug is rapidly and widely distributed throughout the body and is eliminated from plasma with a T ½ of approximately 2 hours. The major metabolites are glucuronide and sulphate conjugates (>80%) which are excreted in urine. Caffeine/metabolites are excreted in human milk, but at therapeutic doses of the product, no effects on the breastfed new-borns/infants are anticipated. Epidemiological studies in human pregnancy have shown no ill effects due to paracetamol used in the recommended dosage.Do not take anything else containing paracetamol while taking this medicine. Talk to a doctor at once if you take too much of this medicine, even if you feel well. This is because too much paracetamol can cause delayed, serious liver damage.