The anticoagulant effect of warfarin and other coumarins may be enhanced by prolonged regular daily use of paracetamol with increased risk of bleeding, occasional doses have no significant effect. Preventative sprays for your nose or throat which prevent viruses from taking hold are a tempting prospect. Phenylephrine Hydrochloride is a sympathomimetic agent and provides relief from nasal congestion due to its vasoconstrictor action. Adults, the elderly and children 16 years and over: Content of one sachet dissolved by stirring in hot water and sweetened to taste.

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Watch out for brands packaging up the same medicine in different boxes geared towards specific symptoms - this is common with pain relief, throat sweets and cough or cold medicines. If vomiting is not a problem, oral methionine may be a suitable alternative for remote areas, outside hospital. The following are some of the side effects known to be associated with paracetamol and phenylephrine. The list of entitlements is long, so check with your pharmacist or GP - or take a look at the NHS flu vaccine guide - to see if you're eligible.Phenylephrine Hydrochloride - Due to irregular absorption and first pass metabolism by monoamine oxidase in the gut and liver, phenylephrine has reduced bioavailability from the gastrointestinal tract. It retains activity as a nasal decongestant when given orally, the drug distributing through the systemic circulation to the vascular bed of nasal mucosa. There is also some evidence that a spoonful of honey dissolved in warm water is actually more effective than medicated products for reducing the frequency and severity of a cough. Get immediate medical advice if you or someone you know takes too much paracetamol, even if you feel well, because of the risk of delayed, serious liver damage.

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Heat-sealed laminate sachet of 40 gsm paper/12 gsm PE extrusion/8 micron aluminium foil/18 gsm Surlyn. When taken by mouth, decongestants such as phenylephrine can also temporarily decrease the production of breast milk with just one or two doses. Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of paracetamol, however, the maximum protective effect is obtained up to 8 hours post-ingestion. a, Is on long term treatment with carbamazepine, phenobarbitone, phenytoin, primidone, rifampicin, St John's Wort or other drugs that induce liver enzymes.In severe poisoning, hepatic failure may progress to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema and death. Hypertensive patients or those who are taking, or have taken in the last two weeks, monoamine oxidase inhibitors, tricyclic antidepressants or beta-blockers (see section 4.

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Due to the phenylephrine content this product should not be used in pregnancy or whilst breast-feeding without medical advice. Despite a lack of significant early symptoms, patients should be referred to hospital urgently for immediate medical attention. Be careful about taking any other paracetamol products in conjunction with combination tablets, as it can be easy to accidentally take more than the recommended dose. This product should not be used during pregnancy or breast feeding unless the expected benefit to the mother justifies the potential risk to the foetus or infant. Any type of sucking sweet and a painkiller should do the trick just as well, and save you some money.You should also avoid taking more than one paracetamol-containing medicine at the same time, as this can easily result in exceeding the maximum dose of paracetamol. If you're taking the anti-cancer medicines imatinib or busulfanyou shouldn't take Beechams cold and flu without first checking with your doctor or pharmacist. Bear in mind that there's no 'cure' for the common cold, so it's more about managing symptoms to help you feel better. There's some evidence that lozenges help with throat pain, but there's not a great deal of evidence to suggest you need a medicated lozenge.