Apply a thin film of Lipsore 5% w/w Cream to theinfected skin, and the skin immediately next to it,using your fingertip. Take care not to rub theinfected skin any more than you need to.

Lipsore 5% w/w cream contains cetyl alcohol and propylene glycol which may cause local skin reactions(skin irritation and redness). 3. Howto use Lipsore 5% w/wCream Lipsore 5% w/w Cream is for use on the skin only. It is not to be taken internally. If you have ever had an allergic reaction to Aciclovir, valaciclovir, propylene glycol or any other ingredients ofthe preparation (see section 6 for a complete list of ingredients). Wash your hands again. Herpes simplex isinfectious and you should try to avoid touching theinfected skin with your hands or with towels, etc.to prevent spreadingthe infection. In this case let your doctor know immediately. He will decide if you should continue with Lipsore 5% w/wCream. Very Rare (< 1/10,000):To work at its best, Lipsore 5% w/wCream shouldbe started as soon as possible after the firstsymptoms of infection appear. Aciclovir is predominantly eliminated via the kidneys, primarily by glomerular filtration and to a lesser extent by tubular secretion. Very common ≥1/10, common ≥1/100 and <1/10, uncommon ≥1/1000 and <1/100, rare ≥1/10,000 and <1/1000, very rare <1/10,000. If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side The required dose of Lipsore 5% IV should be administered by slow intravenous infusion over a one-hour period.

For 24 days, PEG-based aciclovir cream 5 or 10% was applied to the shaved (intact and grazed) skin of guinea-pigs. The treated area corresponded to 10% of the body surface. There were neither systemic nor local toxic symptoms. This is also confirmed by histologic studies and autopsy. According to the test carried out by Draize, who evaluated the allergic sensitising potential of a substance, there were no pathogenic findings.Paediatric Formulary Committee. BNF for Children 2015-2016. London: BMJ Group, Pharmaceutical Press, and RCPCH Publications; 2015. If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines. If any of the side effects get serious, or if you noticeany side effects not listed in the leaflet, please tellyour doctor or pharmacist. In this leaflet:

The New Model from SD Biosensor (the manufacturers of the No.1 selling SD Codefree Blood Glucose Meter) has all the benefits of the Codefree plus it boasts a greater accuracy due to a wider haematocrit (HCT) range of 0-70% and GDH-FAD enzyme technology.

Continue treatment for 4 days. If your cold sore hasn't healed after this time, you can use the cream for up to I0 days in total.

To avoid spreading the infection, wash your hands before and after applying aciclovir. Remember infection can also spread to others. There is no experience of the effect of aciclovir tablets on human female fertility. Aciclovir tablets have been shown to have no definite effect upon sperm count, morphology or motility in man. See Clinical Studies in section 5.2. A post-marketing aciclovir pregnancy registry has documented pregnancy outcomes in women exposed to any formulation of aciclovir. The birth defects described amongst aciclovir exposed subjects have not shown any uniqueness or consistent pattern to suggest a common cause.Two metabolites could be identified in the urine of patients with normal renal function after single dosing with 14C-Aciclovir: 9-carboxymethoxymethylguanine (2-14% of an administered dose) and 8-hydroxy-9-(2-hydroxyethoxymethyl)guanine(<0.2% of a dose). Subjects with normal renal function eliminate 62-91% of an aciclovir dose unchanged and 9-14% as 9-carboxymethoxymethylguanine via the kidneys. If you have any further questions on the use of Lipsore 5% w/w Cream askyour doctor or pharmacist. 4. Possible side Effects People with particularly severe recurrent herpes labialis should be encouraged to seek medical advice. Not recommended for use by patients who know they are immunocompromised e.g. by HIV infection, bone marrow transplant or cancer treatment, except on the advice of a doctor. Such individuals should be encouraged to consult a physician concerning the treatment of an infection.