Frontline Plus Spot-on Large Dog (20-40kg) [6 pack] not only kills fleas and ticks on your pet it also contains active IGR technology that stops flea eggs from hatching and larvae developing in your home. FRONTLINE Plus for Large Dogs is a topical application for the treatment of flea infestations, alone or in association with ticks and/or biting lice in large breed dogs weighing >20 - 40kg. Fipronil kills fleas within 24 hours and ticks (Dermacentor reticulatus, Dermacentor variabilis, Rhipicephalus sanguineus, Ixodes scapularis, Ixodes ricinus, Haemaphysalis longicornis, Haemaphysalis flava, Haemaphysalis campanulata) and lice within 48 hours post-exposure. It has an insecticidal efficacy against new infestations of adult fleas for 8 weeks, and will prevent their multiplication by inhibiting the development of eggs, larvae, and pupae for 8 weeks after application.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal product should be disposed of in accordance with local requirements. This is a fantastic product which is extremely easy to apply giving consistent performance for the full 4 weeks. FRONTLINE PLUS ® for Cats can only be used on cats and ferrets; FRONTLINE PLUS ® for Dogs can only be used on dogs; FRONTLINE ® SPOT ON for Cats can only be used on cats; FRONTLINE ® SPOT ON for Dogs can only be used on dogs and FRONTLINE TRI-ACT ® can only be used on dogs. For information about side effects, precautions, warnings and contraindications please refer to the product packaging and package leaflet. Your pet should be accurately weighed prior to treatment to ensure that the correct Frontline Plus product is used.When used as directed, pets treated with FRONTLINE ® flea and tick treatments do not pose a health risk to children or adults. Treated animals should not be handled until the application site is dry, and children should not be allowed to play with treated animals until the application site is dry. It protects for four weeks and breaks the flea life cycle by killing adult fleas and reducing eggs and larvae.

Excessive salivation, reversible nervous signs (increased sensitivity to stimulation, depression, other nervous signs), vomiting , or respiratory symptoms have also been observed after use. Bathing/immersion in water within 2 days after application and more frequent bathing than once a week should be avoided, as no study has been performed to investigate its effect on product efficacy.It concentrates into the sebaceous glands of the skin and is constantly replenished over the pet’s skin and coat. FRONTLINE PLUS ® for extra-large dogs can be used on dogs over 40 kg – there’s no upper weight limit for this product. FRONTLINE Plus Spot On contains active IGR technology (Insect Growth Regulator) to prevent flea eggs from hatching and larvae developing in the home, providing enhanced household protection. Emollient shampoos can be used prior to treatment, but reduce the duration of protection against fleas to approximately 5 weeks when used weekly after application of the product.