Wang J, Chai S, Zheng G, et al. Expert consensus statement on computed tomography-guided 125I radioactive seeds permanent interstitial brachytherapy. J Cancer Res Ther. 2018;14(1):12–7. Deeply-placed implants should be localised and removed as soon as possible to avoid the potential for distant migration (see section 4.4).

https://www.optionsforsexualhealth.org/facts/birth-control/methods/implant/#1611861248552-ed866897-10d7 Before initiating the removal procedure, the HCP should assess the location of the implant. Verify the exact location of the implant in the arm by palpation. The implant should be inserted subdermally just under the skin at the inner side of the non-dominant upper arm. There have been reports of broken or bent implants, which may be due to external forces applied while in the patient's arm. There have also been reports of migration of a broken implant fragment within the arm. Based on in vitro data, when the implant is broken or bent, the release rate of etonogestrel may be slightly increased. This change is not expected to have clinically meaningful effects. We have historically always used implanter pens when carrying out hair transplant surgery in our clinic. We find patients recover faster and have better quality results with the technique. Whilst the technique is more laborious, we don’t mind and are happy to go the extra mile for our patients Dr Vara, Hair Transplant Surgeon and Director at The Treatment Rooms London Depth, Angulation and Density of Hair TransplantationHuang W, Lu J, Chen KM, et al. Preliminary application of 3D-printed coplanar template for iodine-125 seed implantation therapy in patients with advanced pancreatic cancer. World J Gastroenterol. 2018;24(46):5280–7.

It can sometimes be challenging to use the ICE structure in a way that sounds natural in your contraceptive consultation, but we have provided some examples for each of the three areas below. Ideas Hormonal contraceptives may affect metabolism of certain other active substances. Accordingly, plasma and tissue concentrations may either increase (e.g. ciclosporin) or decrease (e.g. lamotrigine).

References

Limited epidemiological data do not suggest an increased risk of VTE or ATE in women using the implant; however, there have been postmarketing reports of VTE and ATE, in women using etonogestrel implants. It is recommended to assess risk factors, which are known to increase the risk of VTE and ATE. This patient underwent a DHI hair transplant to repair his frontal hairline. He had surgery previously in another hair transplant clinic with poor results. His result shown here is 1 year post his repair surgery in our clinic DHI Hair Transplant Surgery and Implanter Pens

From August 2016 to March 2017, a total of 25 patients underwent seed implantation in our hospital, including 17 male and 8 female patients. The average age was 65 years (64.64 ± 14.12 years), and the age range was 44–87 years. Seven patients had lung tumours, 6 had bone metastases, 2 had pancreatic cancer, 1 had cervical lymph node metastases and 1 had inguinal lymph node metastases, 2 had bladder cancer recurrence, 1 had pelvic metastases, 1 had lung cancer with adrenal gland metastases, 1 had maxillary sarcoma, 1 had lung cancer with liver metastases, 1 had vulvar cancer recurrence, and 1 had liver cancer with brain metastases. The pre-operative physical strength score (Karnofsky performance score, KPS) was > 60, the white blood cells (WBC) count was ≥4.0 × 10 9/L, and the expected survival time was > 3 months. Patients with tumour progression after radiotherapy and chemotherapy or patients who could not receive chemoradiotherapy were included. All patients were aware of their disease status and understood the possible treatment effect and adverse reactions. All patients voluntarily accepted the treatment method and signed a consent form for seed implantation surgery. The study was approved by the Ethics Committee of our hospital. Materials and devices Li J, Zhang L, Xie Q, et al. How many times 125I seed implantation brachytherapy can be repeated for pulmonary metastases: clinical efficacy and complications. J Contemp Brachytherapy. 2019;11(1):35–40. The SPOT Pro planning software used at the RAH allows the user to update the location of the implanted needles in real-time on the treatment planning system and hence automatically recalculate the plan dosimetry, to accurately reflect what was actually implanted. This is important, as the theoretically planned grid positions might not always be practically attainable. There are a few factors which can possibly impede the perfect reproduction of the treatment plan: In the current study, 25 patients with advanced refractory malignant tumours underwent continuous seed implantation, and no serious complications occurred in the entire group, such as implant and distant organ metastases. Thus, although the number of implanted needles was increased, the application of 3D printing technology rendered template-assisted seed implantation accurate, shortened the operative time, and decreased the number of intra-operative needle adjustments; as a result, the complications caused by repeated punctures were decreased. The study further illustrated the feasibility and safety of radioactive 125I seed implantation with 3D template guidance for the treatment of malignant tumours.Turajlic S, Litchfield K, Xu H, et al. Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis. Lancet Oncol. 2017;18(18):1009–21.