Work with anyone affected by mental illness, including families, friends and carers. They also provide a free text-based support service called Textcare. And an online supportive forum community where anyone can share their experiences of mental health.

If you or someone you know is exhibiting suicidal thoughts and behaviours, you should seek immediate help from a doctor or crisis line. If you or someone you know has taken harmful actions, call 999 and ask for an ambulance or go straight to your nearest A&E.

Maytree is a national registered charity based in London. They provide a unique residential service for people in suicidal crisis so they can talk about their suicidal thoughts and behaviour. They offer a free 4 night, 5 day one-off stay to adults over the age of 18 from across the UK. Their aim is to provide a safe, confidential, non-medical environment for their guests

An overdose of dextropropoxyphene may lead to various systemic effects. Excessive opioid receptor stimulation is responsible for the CNS depression, respiratory depression, aspiration pneumonia, miosis, and gastrointestinal effects seen in propoxyphene poisoning. It may also account for mood- or thought-altering effects. In the presence of amphetamine, propoxyphene overdose increases CNS stimulation and may cause fatal convulsive seizures. [18] Urge the person to stay away from alcohol and drug use. Using drugs or alcohol may seem to ease painful feelings, but it makes things worse. It can lead to unsafe behaviors or feeling more depressed. If the person needs help quitting, offer to help find treatment. Self-loathing, self-hatred – Feelings of worthlessness, guilt, shame, and self-hatred. Feeling like a burden (“Everyone would be better off without me”). Schedule daily activities. Activities that calm and comfort you can make a difference — such as listening to music, watching a funny movie or visiting a park. Or try something different. Because physical activity and exercise may reduce depression symptoms, think about walking, jogging, swimming, gardening or trying a new activity.Do not talk down to or be critical of the person. For example, do not tell someone, "Things could be worse" or "You have everything to live for." Instead, ask questions such as, "What's causing you to feel so bad?" "What would make you feel better?" or "How can I help?" Teenage suicide is a serious and growing problem. The teenage years can be emotionally turbulent and stressful. Teenagers face pressures to succeed and fit in. They may struggle with self-esteem issues, self-doubt, and feelings of alienation. For some, this leads to suicide. But there are no additional benefits. If the patient failed the test of full competency – as will be the case for the majority of patients in such circumstances, whose cognitive function will often be affected by the severity of their illness, dementia or other factors — adequate relief of suffering will be obstructed rather than facilitated. To limit appropriate sedation only to those who can consciously demand it would merely increase the burden of harm. In addition, the deliberate taking of life would be experienced as distressing to many members of society and an affront to the traditions of medicine. Stay away from drugs and alcohol. Rather than numb painful feelings, alcohol and drugs can increase suicidal thoughts and the chance you'll harm yourself. Alcohol and drugs can make you more impulsive and more likely to act on feelings to harm yourself. In the Stephen King short story collection Night Shift, the final story of the book, " The Woman in the Room", tells a tale in which the main character contemplates and then finally performs a mercy killing using a drug called "Darvon Complex."

In 2008, the online handbook— The Peaceful Pill eHandbook—was launched, containing video clips on assisted suicide and voluntary euthanasia methods and related issues, but it does not provide "how-to" instructions. The eHandbook is updated bimonthly.If a friend or family member is suicidal, the best way to help is by offering an empathetic, listening ear. Let your loved one know that they're not alone and that you care. Don't take responsibility, however, for healing your loved one. You can offer support, but you can't make a suicidal person get better. They have to make a personal commitment to recovery. Propoxyphene was initially introduced as propoxyphene hydrochloride. Shortly before the patent on propoxyphene expired, propoxyphene napsylate form was introduced to the market. Napsylate salt (the salt of naphthalenesulfonic acid) is claimed to be less prone to non-medical use, because it is almost insoluble in water, so cannot be used for injection. Napsylate also gives lower peak blood level. [24] Because of different molecular mass, a dose of 100mg of propoxyphene napsylate is required to supply an amount of propoxyphene equivalent to that present in 65mg of propoxyphene hydrochloride. Take the person seriously. If a suicidal person says things like, “I’m so depressed, I can’t go on,” ask if they’re having thoughts of suicide. You’re allowing them to share their pain with you, not putting ideas in their head. Severe. Suicidal thoughts. Specific plan that is highly lethal. The person says they will attempt suicide.

Others think that the overall benefit to people of these medications outweigh the risk of suicidal thoughts. At the time, people who drank excessive amounts of alcohol and other substances and take combination dextropoxyphene / acetaminophen (paracetamol) were discussed as needing to take many combination tablets to reach euphoria, because the amount of dextropropoxyphene per tablet is relatively low (30–40mg). The ingested paracetamol—the other component—may then reach liver toxic levels. In the case of alcoholics, who often already have damaged livers, even a relatively small overdose with paracetamol may produce hepatotoxicity, liver failure, and necrosis. This toxicity with the combination of overdosed dextroproxyphene (with its CNS/ respiratory depression/vomit with risk for aspiration pneumonia, as well as cardiotoxicity) and paracetamol-induced liver damage can result in death. Crisis support: text THEMIX to 85258 for crisis support (24 hours a day, every day) - www.themix.org.uk/get-support/speak-to-our-team/crisis-messenger Dextropropoxyphene is contraindicated in patients allergic to paracetamol (acetaminophen) or dextropropoxyphene, and in alcoholics. It is not intended for use in patients who are prone to suicide, anxiety, panic, or addiction.To illustrate why this is so, imagine the case of an elderly man in the last stages of terminal cancer. The disease has spread and is in his bones, lungs, liver and brain. It is incurable and he has, at most, weeks to live. High toxicity and relatively easy availability made propoxyphene a drug of choice for right-to-die societies. It is listed in Dr. Philip Nitschke's The Peaceful Pill Handbook and Dr. Pieter Admiraal's Guide to a Humane Self-Chosen Death. [56] [57] "With the withdrawal of the barbiturate sleeping tablets from the medical prescribing list, propoxyphene has become the most common doctor-prescribed medication used by seriously ill people to end their lives." [56] See also [ edit ] People who have suicidal thoughts can experience them differently. Some might actively be planning to end their lives. Others might have the thoughts without planning to act on them. Get together with others. Create your support network by reaching out to friends, family and people who care about you and are there when you need them. Try to be social, even if you do not feel like it. This will help keep you from becoming isolated.