Other research shows that a diet high in dietary fiber, which encourages butyrate production, could help lower your risk of colon cancer. Designs for Health is a pioneer in the health practicioner space and one of the first to enter with Corebiome® Tributyrin, finding a lot of success. We’re so excited to continue our relationships with them as they help folks get access to gut health. With our Corebiome® Tributyrin, the industry’s first bioavailable form of butryate, Designs for Health Tri-butyrin Supreme™ is well worth the try if you are exploring options on how to get Corebiome® Tributyrin. Here’s what our friends at Designs for Health say: Tributyrin is a novel prodrug of butyrate that is found in milk fat and honey Tributyrin was able to destroy cancer cells in patients with advanced solid tumors [ 96, 97]. There’s the Native American tale that talks about the two wolves that live inside of you. One is good; the other evil. They constantly fight and the one that wins is the one you feed. We suggest feeding the good wolf with good things like fiber for a healthier microbiome. But how do you get enough fiber for a healthy gut? Homeostasis [Balance] is the name of the gut health game According to animal studies, butyrate may potentially protect nerves and brain cells from degenerative disease. In mice, butyrate promoted the survival of nerve cells in mice with amyotrophic lateral sclerosis (ALS), a disease which makes the nerves responsible for movement die off [ 74].

Purified Resistant Starch Powder is the best method to increase butyrate levels, more so than supplements or foods. In mice, butyrate-producing dietary fibers counteracted inflammation and illness caused by bacterial toxins. The inflammatory cytokines inhibited by butyrate included interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-alpha), and interferon gamma (INF-y) [ 29]. Immune Response

INHIBITS ABNORMAL CELL GROWTH

Core to SO many of issues is gut health. Eliminating processed food helps tremendously, but what else can we do to restore gut microbiota?

There’s a huge overlap between cognitive enhancement and recovery from brain damage. Both rely on neurogenesis, a process that replenishes and reshapes the brain. Further research seems to have identified the mechanisms at the heart of this astounding effect. Butyrate inhibits histone deacetylase (HDAC), an enzyme that regulates protein functioning central to the development of cancerous cells. [12] Another study, published in Molecular Cancer in 2010, found that butyrate also downregulates Neuropilin-1 (NRP-1), a gene whose expression has been shown to promote colon cancer. [13] If that’s not enough, there may be yet another mode by which butyrate prevents the growth of cancerous cells. Research published in Mutation Research in 2009 suggests that the SCFA increases the activity of detoxifying enzymes like glutathione-S-transferases (GSTs), a line of genes that help protect cells from carcinogens. [14]

Some supplements may encourage butyrate production, but you should talk to your healthcare provider before taking any. Most supplements use butyric acid and some kind of salt, but they haven’t been proven to be beneficial.