Not everybody’s body is the same – and things can change depending on your build, health, and dinner. Here are a number of external factors that may make Viagra (or generic unbranded Sildenafil) a little slower to take effect – or things that may affect its efficacy overall. How Diet Affects Viagra’s Effectiveness Mullin R (20 June 2005). "Viagra". Chemical & Engineering News. 83 (25) . Retrieved 20 August 2008.

Boolell M, Allen MJ, Ballard SA, Gepi-Attee S, Muirhead GJ, Naylor AM, etal. (June 1996). "Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction". International Journal of Impotence Research. 8 (2): 47–52. PMID 8858389.

Other medications: Taking certain other medications at the same time as Viagra can impact its effectiveness – so it’s important to make any clinician aware of what treatments you are taking. You should never take Viagra alongside other ED medications at the same time. This is quite common. Most patients will experience a worsening of their erections after they’ve been on Viagra for a while,” says Hatzichristodoulou. “They take Viagra for five, six, 10 years, and some days they feel that there is little improvement in function.” Viagra patent tossed out by Supreme Court: Decision allows generic versions of drug to be produced". CBC News. 8 November 2012 . Retrieved 14 November 2012. Sung BJ, Hwang KY, Jeon YH, Lee JI, Heo YS, Kim JH, etal. (September 2003). "Structure of the catalytic domain of human phosphodiesterase 5 with bound drug molecules". Nature. 425 (6953): 98–102. Bibcode: 2003Natur.425...98S. doi: 10.1038/nature01914. PMID 12955149. S2CID 4404590.

You should take the pill at the same time every day, unless you are on a 7 day pill break. It can be less effective if you do not take it as prescribed. The combined oral contraceptive pill or ‘the pill’ has two types of female hormones in it. These are called oestrogen and progesterone. Your body makes these hormones naturally in your ovaries. The pill changes the amounts of these hormones that your body produces, and stops your ovaries from releasing an egg each month. How do you take the combined pill? This genetic location is part of a pathway which is involved in a number of different systems in the body, from pigmentation to weight to sexual function,” explains project leader Eric Jorgenson. “But what is exciting about this, is that it seems to be very specific to sexual function, which would make it possible to target this location and not disturb anything else in the body. But there’s a long way to get there. We need to understand the exact part of the brain where this switch is active, and then try targeting it in mice.” Tadalafil provides a wider window of opportunity. So, if you and your partner are looking for a bit more spontaneity, this option might be a better fit. Somra G (31 August 2015). "Online pharmacies suspected of counterfeit drug sales". CNN . Retrieved 10 January 2017.

Table of comparison

Although there are other options with different active ingredients, the blue pill is the best medication to take for planned sexual encounters. In 1992, Pfizer filed a patent covering the substance sildenafil and its use to treat cardiovascular diseases. [111] This would be marketed as Revatio. The patent was published in 1993 and expired in 2012. The patent on Revatio (indicated for pulmonary arterial hypertension rather than erectile dysfunction) expired in late 2012. Generic versions of this low-dose form of sildenafil have been available in the U.S. from a number of manufacturers, including Greenstone, Mylan, and Watson, since early 2013. [112] Health care providers may prescribe generic sildenafil for erectile dysfunction. [109] For a time, the generic was not available in the same dosages as branded Viagra, so using dosages typically required for treating ED required patients to take multiple pills. [109] Taking the mini pill can change your period. You might get no period, a lighter period, or a heavier period. Contraceptive phasic pill