In The Originals, Elena is still in no humanity zone. Damon and Stefan are wondering what to do when Katherine walks in. She says Hayley, the werewolf girl, will get Klaus out of their lives for good. Later, Damon feeds Elena blood with vervain in it. He wants her to feel angry or mad or scared. Elena says it'll be interesting to see who breaks first. This prompts Klaus to make a big speech about how he gave Stefan's life purpose by giving him something to hate. He's so full of himself that Stefan can't help but try to kill him. Klaus easily squashes his attempt. Then, Rebekah frees Damon and tells Stefan that if he turns in the remaining three stakes she and Klaus will let them live. Later, Damon goes over to Alaric's to get the last stake but Alaric can't find it. Its been moved from its hiding place behind the bookshelf. After snarking Alaric for hiding it in such a cliched place, Damon asks if Alaric is really telling him that he is missing a stake that could kill his line of vampires. Alaric tells him that is what he's saying. In Total Eclipse of the Heart, Damon is first seen in Salvatores living room, when he is sleeping on the couch. Stefan comes to him and asks about this mess he has done to the room and about Aaron's corpse in his car. Damon and Enzo are telling Stefan that they are going after whole Augustine institution, to get the full revenge on them. Stefan says to Damon that he is better than this, but Damon says that he is better like this.

In Promised Land, it has been four days since the travelers took Stefan and Elena and Damon has been desperately searching for them. He is torturing a Traveler inside a guy named Sykes. He asks him where Markos is as the Travelers want to break the witch curse so they can settle, it also reverses the witch's spell that created vampires and they all die. Damon ungags the Traveler long enough for him to say there's nothing they can do to stop Markos. Later, he gets a call from Stefan who informs him that he and Elena have managed to free themselves from the Travelers but don't know where they are. When Stefan tells him that he has Elena hunting squirrels, Damon jokes that Elena will shoot Stefan's eyes. Damon tells him that he will find and kill Markos and asks him to have both him and Elena return home safely. The Five, shows Damon tasking Stefan with learning more about the Vampire Hunter, Connor while Damon decides to accompany both Bonnie and Elena to College. This trip is ostensibly about teaching Elena the 'hunt': how to catch, feed and erase. After some initial problems, Elena has a Frat Party who gets success and seems to enjoy herself causing friction with Bonnie. She leaves the party and later states that she does not want to be like Damon. In the next episode, she begins to believe that Stefan is lying to her and takes things into her own hands to kill the vampire hunter who is holding her brother, Matt, and April captive. She does and begins to suffer from hallucinations at the end of the episode. After asking Stefan why he wants to cure Elena, Damon tells him that he loves Elena as a vampire or human. Damon hands over the Salvatore Boarding House to Caroline, which she then turns into the Salvatore Boarding School for the Gifted, where Alaric's daughters are staying. Caroline also receives a gift from Klaus, saying that he will always be waiting for her no matter how long it takes. He then hurries to Whitmore and finds Enzo with Stefan and Elena tied with vervain ropes. He reveals to them that on November 8, 1960, he got a message at the house that a woman wanted to interview him. He didn't know she was Enzo's Maggie. She wanted revenge from him for leaving Enzo behind in the fire but she didn't stood a chance against Damon. Damon had killed her and made it look like Stefan did it because of his grudge of Stefan not coming to get him the five years he was in Augustine captivity. Damon asks Enzo to resolve this among themselves and not to include others. Enzo confesses he can't hate Damon because then he has nothing left. He realizes there is another option and switches off his humanity.As the first vampires, the Mikaelson family have the oldest known daylight rings spelled by Esther. In Bloodlines, Damon starts of the episode with a bang when he rescues Elena from her crashed SUV. When she awakens, Damon reveals that they're in Georgia. He takes her to Bree's Bar, where he reveals that he's known Bree since she was a college freshman, and that she's a witch. While Elena's on the phone, Damon questions Bree about another way to open the tomb, and he's disappointed to find that there is no other way. When she calls Stefan, Damon goes outside and asks if she's okay, to which she responds, cautiously, "Don't pretend to care." Inside, the two both eat a plate of fries with a burger while Damon explains that Elena can't possibly be descended from Katherine, because Katherine never had a child. Damon joins Elena and Bonnie outside. Bonnie accuses him of wanting Elena to be like him, and he argues that she already is and needs to learn to revel in the feed; not hating herself and enjoying it will be the only way she, like him, can make feeding fun and not get carried away. Damon walks away, leaving Elena crying about what had happened. He accompanies her home and she apologizes for letting things get out of hand at the party, confessing that she hates that, deep down, she agrees with Damon's point of view. She starts to say she doesn't want to be that way, and Damon finishes her sentence to say she doesn't want to be like him. When Stefan opens the door, Damon leaves. Damon Salvatore is a vampire, turned by Katherine Pierce 145 years prior to the series' debut. He is the son of late Giuseppe Salvatore, ripper Lily Salvatore and older brother of Stefan Salvatore. Damon is portrayed as charming but cruel, taking pleasure in killing and feeding on humans, while Stefan satisfies his vampiric hunger by feeding on animals.

In We All Go a Little Mad Sometimes, Damon arrives at the Gilbert house after Elena called him, though he wonders why she asked him to come and not Stefan. Elena admits she doesn't trust Stefan at the moment, and Damon in turn admits that he called Stefan as the younger Salvatore walks in the front door. After Elena finishes showering, she has another hallucination, and this time she imagines that Damon is Connor. She bolts out of the house, where Klaus grabs her and speeds off. Bonnie meets up with Damon and Stefan and they ask for her help in breaking the curse Elena is under. She says the spirits won't let her do that kind of magic to break the curse, but she suggests that Shane might be able to help.In Season Five, he discovered Enzo's undead status and they became friends once again. However, once " Elena" broke up with him, he put an end to his diabolical plan against the Whitmore family and was then injected with a dangerous compound by Wes Maxfield, causing him to become the only Augustine Vampire in existence. This injection caused him to crave vampire blood and he would not be able to stop feeding until he had killed. He was later cured, thanks to Enzo, Stefan, and Caroline's actions. Due to the Other Side collapsing, Damon gave up his life to save his loved ones and this caused Elena, Stefan, and Alaric much grief. Although the Originals cannot be destroyed by the sun, the sun will burn them before they heal. Without their rings in the public, they would expose themselves as vampires. Since they were the first of their kind, only the originals owned daylight rings, and for many decades, it kept up, until the spell to create the rings was slowly revealed, and more and more vampires started to wear Daylight Amulets. Either by form of rings, or other jewelry. Damon beats the truth out of Stefan by staking him in the stomach several times. Stefan reveals that he saved his brother because Klaus' hybrids would have killed Damon. After telling him to stop saving his life, Damon leaves. Later, Stefan reveals that the dead witches are hiding the coffins, making them invisible for Klaus. After he came to Elena's house, she gets Damon to compel Jeremy. Damon sits down and compels him to leave town to go to Denver. Outside, he and Elena discuss if it was right to compel Jeremy and they also talk Stefan. Damon thought he doesn't have to feel guilty anymore and is about to go. Then, however, he says he only has one thing to feel guilty about now and they share a passionate kiss.