de Gouw, H. W., Verbruggen, M. B., Twiss, I. M., and Sterk, P. J. Effect of oral L-arginine on airway hyperresponsiveness to histamine in asthma. Thorax 1999;54(11):1033-1035. View abstract.

With this in mind, anyone interested in taking L-arginine needs to talk with their doctor about the potential benefits and risks before using it. However, most studies investigating this relationship have found that L-arginine is not beneficial for improving athletic performance ( 8, 9, 10, 11). A daily dose varies depending on what you’re being treated for – typically, it’s 2 to 8g per day but can be higher. For example, for chest pain due to coronary artery disease, the dosage has been determined as 3 to 6g three times per day for one month. Know the overdose risks Amore, A., Gianoglio, B., Ghigo, D., Peruzzi, L., Porcellini, M. G., Bussolino, F., Costamagna, C., Cacace, G., Picciotto, G., Mazzucco, G., and . A possible role for nitric oxide in modulating the functional cyclosporine toxicity by arginine. Kidney Int. 1995;47(6):1507-1514. View abstract. Additionally, although the increased demand for arginine during pregnancy can be provided through diet, protein or individual amino acid supplements may be necessary under certain circumstances.Herbs and supplements that thin the blood: clove, angelica, garlic, ginkgo biloba, Panax ginseng, turmeric, etc. Cereda, E., Gini, A., Pedrolli, C., and Vanotti, A. Disease-specific, versus standard, nutritional support for the treatment of pressure ulcers in institutionalized older adults: a randomized controlled trial. J Am Geriatr.Soc 2009;57(8):1395-1402. View abstract. How does l-arginine help sexual function? Studies not only show it’s ability to increase penile blood flow for sustained erection, but it may also increase sperm count and motility (x, x). Studies also suggest that it may increase blood flow and promote stimulation to female sexual organs (x). Synthesizing Citrulline There are several additional areas that researchers are interested in exploring regarding L-arginine and its effects on the human body.

If you can’t find a product tested by a third party, look for one manufactured at a cGMP facility to ensure that it meets FDA quality standards.

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Brittenden, J., Heys, S. D., Ross, J., Park, K. G., and Eremin, O. Natural cytotoxicity in breast cancer patients receiving neoadjuvant chemotherapy: effects of L-arginine supplementation. Eur.J Surg.Oncol. 1994;20(4):467-472. View abstract. Additionally, it acts as a precursor to other amino acids, including glutamate, proline, and creatine, and is essential for the health and functioning of your immune system.