Nurofen Plus recalled amid sabotage fears". London: The Daily Telegraph. 26 August 2011. Archived from the original on 27 August 2011 . Retrieved 17 November 2011.

Masking of symptoms of underlying infections. Nurofen Plus can mask symptoms of infection, which may lead to delayed initiation of appropriate treatment and thereby worsening the outcome of the infection. This has been observed in bacterial community acquired pneumonia and bacterial complications to varicella. When Nurofen Plus is administered for fever or pain relief in relation to infection, monitoring infection is advised. In non-hospital settings, the patient should consult a doctor if symptoms persist or worsen.

Who may not be able to take ibuprofen

Side effects from codeine are theoretical warnings based on drug class. No clinical data is available to determine frequency. Therefore, Nurofen Plus is contraindicated for use during breastfeeding. However, in circumstances where a breastfeeding mother requires codeine therapy, breastfeeding should be suspended and alternative arrangement should be made for feeding the infant for any period during codeine treatment. Breastfeeding mothers should be told how to recognize signs of high morphine levels in themselves and their babies. For example, in a mother, symptoms include extreme sleepiness and trouble caring for the baby. In the baby, symptoms include signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing difficulties, or limpness. Medical advice should be sought immediately.

If you have not told your doctor about any of the above, tell him/her before you start taking Nurofen Plus. Nurofen Plus should be administered with caution in patients who have recently had gastrointestinal surgery, paralytic ileus, as codeine may reduce gastrointestinal motility. Nurofen Express Maximum Strength 400mg Tablets contain ibuprofen as sodium dihydrate. For mild to moderate pain and fever. See the information below and, if you need to, ask your doctor or pharmacist if you have any further questions about side effects. Less serious side effects Less serious side effectsUsing Nurofen Plus with alcohol may result in severe drowsiness, decreased awareness, breathing difficulties, coma and death. Withdrawal Oligohydramnios and neonatal renal impairment. Use of NSAIDs from about 20 weeks gestation may cause neonatal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.

Use with concomitant NSAIDs, including cyclo-oxygenase-2 specific inhibitors - increased risk of adverse reactions. The list of the following adverse events relates to those experienced with ibuprofen and codeine (maximum of 1200 mg ibuprofen per dayDuring the third trimester, all prostaglandin synthesis inhibitors may expose the foetus to cardiopulmonary toxicity (with premature closure of the ductus arteriosus and pulmonary hypertension) and renal dysfunction, which may progress to renal failure with oligohydramnios. At the end of pregnancy, prostaglandin synthesis inhibitors may expose the mother and the neonate to possible prolongation of bleeding time and inhibition of uterine contractions, which may result in delayed or prolonged labour.