The medicine helps with your brain activity. It can help improve your attention, help you concentrate, and make you less impulsive. Cerebral vasculitis appears to be a very rare idiosyncratic reaction to methylphenidate exposure. There is little evidence to suggest that patients at higher risk can be identified and the initial onset of symptoms may be the first indication of an underlying clinical problem. Early diagnosis, based on a high index of suspicion, may allow the prompt withdrawal of methylphenidate and early treatment. The diagnosis should therefore be considered in any patient who develops new neurological symptoms that are consistent with cerebral ischemia during methylphenidate therapy. These symptoms could include severe headache, numbness, weakness, paralysis, and impairment of coordination, vision, speech, language, or memory. Misuse of stimulants of the central nervous system may be associated with sudden death and other serious cardiovascular adverse events. Please look at the leaflet inside your medicine box, or ask a doctor or pharmacist, if you want to know whether you are getting a side effect from your medicine.

The pros and cons of a small evening dose of immediate-release methylphenidate versus disturbances in falling asleep should be considered. It is important not to break or chew the slow-release methylphenidate tablets or capsules. This is because they have a special system in them to deliver the medicine into your body over a few hours, which could be damaged if you chew or break them. There is a risk of sudden blood pressure increase during surgery. If surgery is planned, methylphenidate treatment should not be used on the day of surgery.Some side effects could be serious. If you have any of the side effects below, see a doctor straight away: If you or your child is taking other medicines, methylphenidate may affect how well they work or may cause side effects. Tell your doctor if you or your child is taking medicines to treat: Dark violet opaque capsule body/dark violet opaque capsule cap (19.4 mm) containing white and blue pellets. The results of the first study (EMMA) reveal that gender-specific differences in the response to methylphenidate and the possibility that women could benefit from lower doses cannot be ruled out. This study demonstrated efficacy in men solely in the highest dose range with MPH > 0.7 mg/kg body weight. In women, however, efficacy was demonstrated even in the low (< 0.3 mg/kg body weight) and mid dose range (0.3-0.7 mg/kg body weight). With respect to reduction in symptoms, women in the high dose group showed no significant effect and, with respect to response rate, efficacy was comparable with that in lower dose groups.

Aqua, Sodium Laureth Sulfate, Sodium Chloride, Cocamidopropyl Betaine, Cocamide DEA, Glycol Distearate, Cocamide MEA, Laureth-10, Piroctone Olamine, Glycerin, Parfum, Citric Acid monohydrate, Methylchloroisothiazolinone, Methylisothiazolinone, Benzyl Alcohol, Sodium Shale Oil Sulfonate (Ichthyol Pale). Balení Methylphenidate treatment is not indicated in all patients with ADHD and the decision to use the medicinal product must be based on a very thorough assessment of the severity and chronicity of the patient's symptoms. When treatment of children is considered, assessment of the severity and chronicity of the child's symptoms should be related to the child's age (6 - 18 years). Methylphenidate is a central nervous stimulant, sometimes called a CNS stimulant, which makes more noradrenaline and dopamine available in your brain. When treating patients with overdose, allowances must be made for the delayed release of methylphenidate from Medikinet XL. during treatment with non-selective, irreversible monoamine oxidase (MAO) inhibitors, or within a minimum of 14 days of discontinuing those medicinal products, due to risk of hypertensive crisis (see section 4.5)It is necessary to take Medikinet XL with or after breakfast. The food influence takes effect and shows a significant and relevant retardation. This justifies the posology to be taken with food. A recommendation in relation of type of food is not necessary. Administration without food can have a risk of dose dumping. Treatment must be initiated and supervised by a doctor specialized in the treatment of ADHD such as an expert paediatrician, a child and adolescent psychiatrist or an adult psychiatrist. Adult patients who have shown clear benefit from treatment with Medikinet XL in childhood and/or adolescence may continue treatment with Medikinet XL into adulthood, initially at the same daily dose (mg/day). Whether or not a dose adjustment depending on efficacy and tolerability is necessary or possible must be reviewed regularly. Methylphenidate is not recommended for use during pregnancy unless a clinical decision is made that postponing treatment may pose a greater risk to the pregnancy.

Each modified-release capsule, hard contains 10 mg methylphenidate hydrochloride equivalent to 8.65 mg methylphenidate. as well as taking this medicine you will also get help with ways to you cope with your ADHD such as talking to ADHD specialists. There are also a growing number of people who are using methylphenidate as a ‘performance-enhancer’ to help them work harder or revise for exams.Caution is recommended when administering methylphenidate with dopaminergic active substances, including antipsychotics. Because a predominant action of methylphenidate is to increase extracellular dopamine levels, methylphenidate may be associated with pharmacodynamic interactions when co-administered with direct and indirect dopamine agonists (including DOPA and tricyclic antidepressants) or with dopamine antagonists including antipsychotics. Height (children), weight and appetite should be recorded at least 6 monthly with maintenance of a growth chart. Patients who are not growing or gaining height or weight as expected may need to have their treatment interrupted. Chronic abuse of methylphenidate can lead to marked tolerance and psychological dependence with varying degrees of abnormal behaviour. Frank psychotic episodes can occur, especially in response to parenteral abuse.