Progressive severity of renal impairment is associated with decreased total clearance of nicotine. Nicotine clearance was on average decreased by 50%, in subjects with severe renal impairment. Raised nicotine levels have been seen in smokers undergoing hemodialysis. Tutti Frutti Flavour liquid (contains orange oil, orange oil terpenes, isoamyl butyrate and citral) For those using this product for the first time or those who have not used the spray for 2 days, they must first prime the spray pump. The pharmacokinetics of nicotine has been extensively studied, and variations in delivery format have been found to have significant effects on rate and extent of absorption.

Step 3 - Nicorette® Invisi 10mg Patch - Once you've completed Step 2, you can reduce your patch strength to 10mg for the final 2-4 weeks (depending on your quit plan). Increased frequency of aphthous ulcer, cough and nasopharyngitis may occur after abstinence from smoking. The causality is unclear. Nicotine should be avoided during breast-feeding The relatively small amounts of nicotine found in breast milk during NRT use are less hazardous to the infant than second-hand smoke. Intermittent dose forms would minimize the amount of nicotine in breast milk and permit feeding when levels were at their lowest.This product may cause adverse reactions similar to those associated with nicotine given by other means, including smoking and vaping, and these are mainly dose-dependent. This product should be used whenever the urge to smoke or vape is felt or to prevent cravings in situations where these are likely to occur. When you stop smoking or cut down the number of cigarettes you use, you might experience cravings to smoke or unpleasant withdrawal symptoms as your body misses the nicotine it s used to absorbing. This can be a sign that your body is dependent on nicotine. Coating contains xylitol, acacia, titanium dioxide (E171), tuttifrutti QL84441, quinoline yellow AI lake (E104), carnauba wax, purified water

Nicorette ® Microtabs only come in one strength but vary in dosage depending on your daily smoking habits: Nicorette ® Lozenges are available in two strengths – 2mg or 4mg. The 2mg lozenge is suitable if you smoke 20 or less cigarettes a day, while 4mg is best for smokers who smoke more than 20 cigarettes per day. When used as directed, symptoms of overdose with nicotine may occur in patients with low pre-treatment nicotine intake or if other sources of nicotine are used concomitantly. This absorption should relieve any unpleasant withdrawal symptoms and help stop your urge to smoke;Use your thumb to slide down the button until you can push it lightly inwards. Don't push too hard. Use 1 or 2 sprays when you would normally have smoked or vaped or if cravings emerge. If after the first spray cravings are not controlled within a few minutes, a second spray should be used. If 2 sprays are required, future doses may be delivered as 2 consecutive sprays. Children aged between 12 to 18 years should consult with a doctor, nurse or pharmacist before starting to use this product. Nicotine passes to the foetus and affects its breathing movements and circulation. The effect on the circulation is dose-dependent. However, if the mother cannot (or is considered unlikely to) quit without pharmacological support, NRT may be used as the risk to the fetus is lower than that expected with smoking tobacco. Stopping completely is by far the best option but if this is not achievable this product may be used in pregnancy as a safer alternative to smoking. Because of the potential for nicotine-free periods, intermittent dose forms are preferable, but patches may be considered as an alternative if there is significant nausea and/or vomiting. If patches are used they should, if possible, be removed at night when the fetus would not normally be exposed to nicotine. Core gum contains chewing gum base, containing butylated hydroxy toluene (E321), xylitol, peppermint oil, anhydrous sodium carbonate, sodium hydrogen carbonate, acesulfame potassium, levomenthol, light magnesium oxide, talc

Core contains mannitol (E421), xanthan gum (E415), winterfresh flavour, sodium carbonate anhydrous, sucralose (E955), acesulfame potassium (E950), magnesium stearate (E470b) Nicorette cools 4mg lozenge is used to relieve/and or prevent withdrawal symptoms and reduce the cravings you get when you try to stop smoking or when cutting down the number of cigarettes you smoke. It provides a safer alternative to smoking for both the individual and those around them. However it can be used in a number of different ways, either to completely replace all your cigarettes, or if you do not feel ready to stop smoking completely, to replace certain cigarettes and therefore help you to cut down the number of cigarettes you smoke. It may also help increase your motivation to quit. Requires willpower.

With dual support, you're more likely to quit for good

Lozenge – Suitable if you smoke 20 cigarettes or less per day. Available in both Nicorette® Cools and Nicorette® Fruit Lozenges. The pharmacokinetics of the mouth spray has been studied in 4 studies. The studies included 141 subjects. Symptoms: Symptoms of overdose with nicotine from this product may occur in smokers/vapers who have previously had a low nicotine intake from cigarettes/e-cigarettes or if other sources of nicotine are used concomitantly with this product. You are more likely to quit smoking/vaping when using this product with help from your pharmacist, doctor, a trained counsellor or a support programme. Nicorette® Inhalator works to relieve cravings and nicotine withdrawal symptoms associated with a dependence on tobacco. It s a form of Nicotine Replacement Therapy (NRT) that provides a low level of nicotine to help reduce withdrawal symptoms without any of the tar, carbon monoxide and other chemicals contained in tobacco smoke.