The quality by design initiative (QbD) of the U.S. Food and Drug Administration requires a process to be controllable and predictable. Theories and methods to characterize powder mixture have facilitated the implementation of QbD approaches to predict flow properties of powder mixture. For example, QbD approach is shown to be useful for predicting flow performance and finding design space during formulation development. [14] The formation of interactive mixtures cannot automatically be assumed, especially if smaller carrier particles [8] or a greater proportion of fine particles [9] [10] are used. If an interactive mixture is to be formed, it is necessary that enough force is exerted by the carrier particles during dry mixing to break up the aggregates formed by the fine particles. Adhesion can then be achieved if the adhesive forces exceed the gravitational forces that otherwise lead to separation of the constituents. [3] Applications [ edit ] A British, 100-year-old company manufactures and supplies the global baking market with high quality produce. They supply a wide range of customer types from individual craft bakers to high street and supermarket chains.

In combination with an Alfa Laval Rotary Jet Mixer , the Hybrid Powder Mixer is a critical component of a highly efficient cleaning-in-place (CIP) system. The powder mixer is available as a stationary or as a mobile unit. The mixing equipment – Alfa Laval Hybrid Powder Mixer and and Rotary Jet Mixer – is key to getting the proper number of SKUs and the formulations. Automation enables us to eliminate human error, which ensures safety and a very high quality level of the final product.’ Our powder mixers can realize the most diverse mixing applications for the most diverse industries. These include all types of food powders, powders for pharmaceuticals, powdered raw materials for cosmetics, chemical or even metal powders, vitamin powders or minerals for animal feed, color powders for plastics production, powders for 3D printers, and also ultrafine dusts. MIXACO powder mixers mix all kinds of powder premixes.

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Winkworth is the UK’s largest industrial manufacturer of mixers, engineering bespoke mixing solutions across any scale of production for the food, chemical, pharmaceutical, ceramic, metal and plastic industries. Get In Touch J. Bridgewater (1976). "Fundamental powder mixing mechanisms". Powder Technol. 15 (2): 215–236. doi: 10.1016/0032-5910(76)80051-4. When adding the powder to the liquid, the powder is added via a funnel. When the C-ball valve under the funnel is opened, the injector positioned under the valve creates vacuum in the funnel outlet, drawing the powder into the rotor-stator mixer and pre-blends the products. The rotor/stator (single rings) creates the main shear, dynamically and efficiently blending powder and liquid into a homogeneous mixture. CASE STUDY How Matcon Transformed Production Capabilities of a Top British Baking Business "The new plant means we can produce an innovative range of pre-mixed ingredients, many of which will be fresh to the UK.” Whether you require a single unit of equipment for installation into an existing system or the design, manufacture, installation and commissioning of a complete large-scale turnkey system, we can help.

Interactive mixtures for example can be used in the manufacturing of tablets [11] enhancing the dissolution of poorly soluble drugs [12] or for nasal administration. [3] One common application is for inhalation therapy, where the concept has been used in the development of alternatives to pressurised metered dose inhalers. [13] With worldclass performance and unparalleled longevity, amixon ® mixing machines are built for industry leaders. Our engineers design and project-manage major industrial installations in many sectors including chemical, mining, additive manufacturing, aerospace, food and pharmaceutical, and deliver equipment which achieves product consistency and homogeneity. Generally, space in a factory comes at a premium, there is never enough space and you certainly don’t want to waste it. If you need to buy multiple industrial mixers to cover the range of batch sizes you produce, then these will all take up valuable room on the factory floor. Depending on the product you are producing, the industrial mixer may need to be housed in a 'clean room', which is expensive to construct and maintain. If you have multiple mixers then the costs of these 'clean rooms' spiral.If you need the flexibility to handle smaller batches, then a cone screw blender or tumble blender will be the most suitable as they can still operate efficiently with low fill levels. Ribbon blenders normally need to be filled to 40-50% of the rated capacity. Here we advise you on the best, most flexible blending solution to suit your manufacturing needs. Why is flexibility important?