Most fluoride-based toothpastes contain a concentration of at least 1,000 parts per million (ppm) of fluoride. For people with severe tooth decay, a dentist may recommend a toothpaste with a concentration of up to 5,000 ppm. When you’re shopping for toothpastes, you want to make sure that you are looking for ingredients that make you healthier,” says Erinne Kennedy, DMD, a dentist and spokesperson of the American Dental Association (ADA). Dr. Kennedy also recommends looking for active ingredients like fluoride and hydrogen peroxide, which will keep your mouth clean and free from disease. Johannsen A, Emilson CG, Johannsen G, Konradsson K, Lingström P, Ramberg P. Effects of stabilized stannous fluoride dentifrice on dental calculus, dental plaque, gingivitis, halitosis and stain: A systematic review. Heliyon. 2019;5(12):e02850. doi:10.1016/j.heliyon.2019.e02850 If you have any special dental needs—for example bleeding gums or sensitive teeth—you should choose a toothpaste formulated for that reason. Many people who fall into this category find traditional toothpastes too harsh for their needs. Surfactant: Most Americans are accustomed to sudsy toothpaste. Sodium lauryl sulfate (SLS) creates the foaming action in conventional toothpastes. Some dentists believe it helps to clean teeth and the mouth more thoroughly.

Those patients with sensitive teeth should look for brands like Sensodyne that incorporate potassium nitrate into their toothpaste formulas, as potassium nitrate helps to soothe inflamed nerves,” Dr. Kunen suggests. If you're unsure which toothpaste will best fit your individual needs, ask your dentist for guidance. We researched dozens of toothpastes and evaluated them for key ingredients, flavor, cavity prevention and other dental benefits, and price. A dentist from our Medical Expert Board also reviewed the contents of this article for medical accuracy surrounding dental hygiene and the efficacy of different active ingredients in toothpastes. Calculus is invariably covered with plaque on its surface. Calculus promotes the retention of dental plaque and may increase the rate of plaque formation. Its porosity can serve as a reservoir for periodontal pathogens and can retain noxious bacterial components such as endotoxin.[ 4 , 5] All subjects received an evaluation of their oral soft/hard tissues by the dental examiner. This examination included an evaluation of the soft and hard palate, gingival mucosa, buccal mucosa, mucosa-gingival fold areas, tongue, sublingual and submandibular areas, salivary glands, and the tonsillar and pharyngeal areas. Candidates were examined by the examining dentist to identify those subjects who demonstrate the presence of supragingival calculus. The scoring procedure used to evaluate calculus formation was the Volpe-Manhold calculus index which uses a standardized and calibrated (in millimeters) periodontal probe to measure supragingival calculus formation in three planes (mesial, midline, distal) of the lingual surfaces of the six lower anterior teeth. Adding the 18 measurements of six teeth constitutes, a total Volpe-Manhold score for each subject.[ 6 , 7] Hydrogen Peroxide: Hydrogen peroxide removes both surface and intrinsic stains, leaving noticeably brighter, whiter teeth.

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Betel leaf contains volatile oil (eugenol, cadinene, carvacrol, caryophyllene, chavitbetol, chavicol, estragole, amino acids, pyridine alkaloids, sitosterols, tannins, stigmasterol, Vitamin C, oxalic acid, malic acid, and inorganic elements like fluoride and iron).[ 16] Further betel leaf possesses anti-bacterial, anti-cariogenic, anti-inflammatory, antifungal, antiprotozoan, anti-allergic, antidiabetic, hepatoprotective, anti-ulcer, cardioprotective, antihyperlipidemic, anti-platelet, and immunomodulatory properties.[ 17] Xylitol: Another beneficial ingredient often found in toothpaste is xylitol. It's a sweetener that “not only makes toothpaste taste good, it helps eradicate bad bacteria that cause tooth decay,”

Recently, there has been a growing interest in natural products. People's interest has been shifted from synthetic toothpaste to herbal toothpaste. Herbal toothpaste does not contain any artificial colors or flavors that many of the regular toothpaste have. Artificial colors and flavors of the toothpaste are also giving birth to many diseases and health-related issues. The demand for herbal toothpaste suppliers has risen due to the great advantages which are associated with this toothpaste type. There are a number of brands of herbal toothpaste on the market. Abhaibhubejhr is a widely known herbal-based toothpaste containing Guava leaves, Betel vine leaves, and Mangosteem peel for which medicinal properties are claimed. However, many of the health claims made for them have not been clinically proven. Test phase: Oral soft/hard tissue and calculus examination, randomization of subjects, oral prophylaxis and toothpaste use at home Inclusion characteristics included good general health, male and female subjects, aged 18–70, inclusive, scoreable lower six anterior teeth free of large restorations or dental prosthetic crowns, a Volpe-Manhold calculus index score of at least 10, and available for the 20-week duration of the study. As the global leader in Oral Care we continue to be committed to making the best scientific and technology advances available to all

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This study was approved by the Faculty of Dentistry, Mahidol University Institutional Review Board (COA. No.MU-DT/PY-IRB 2012/016.1204). Adult subjects from the Faculty of Dentistry, Mahidol University, Thailand, signed an informed consent form and were screened by the examining dentist to identify those subjects who meet the inclusion characteristics and demonstrate a tendency to form calculus. The first 150 subjects who meet the inclusion/exclusion were entered into the pretest phase of this double-blind, randomized, parallel clinical study.

Fiorillo L, Cervino G, Herford AS, Laino L, Cicciù M. Stannous Fluoride Effects on Enamel: A Systematic Review. Biomimetics (Basel). 2020;5(3):41. doi:10.3390/biomimetics5030041

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There are different types of fluoride, but stannous fluoride and sodium fluoride are most commonly used in toothpaste. Stannous fluoride acts as an antibacterial agent, which can help eliminate bad breath and plaque buildup. It can also help reduce tooth hypersensitivity when brushing. Sodium fluoride strengthens teeth and helps protect them from decay and cavities. Fluoride has been a key component of toothpaste for over 50 years, targeting the tooth itself to help make it stronger and working by helping to prevent mineral loss and enhance mineral gain by being incorporated into the tooth as fluorapatite. However, it has proven to help protect against cavities to an extent, but not enough to eradicate them. With the incorporation of arginine, Colgate has established a toothpaste technology that targets the true cause of cavities, the plague germs, a technological advance that should be considered the new gold standard for cavity protection worldwide.