The most compelling insight of that day was that this awesome recall had been brought about by a fraction of a gram of a white solid, but that in no way whatsoever could it be argued that these memories had been contained within the white solid. Everything I had recognized came from the depths of my memory and my psyche. I understood that our entire universe is contained in the mind and the spirit. We may choose not to find access to it, we may even deny its existence, but it is indeed there inside us, and there are chemicals that can catalyze its availability.” Shortly after gaining traction in the underground psychotherapy community, 2C-B became popular in the recreational drug scene. It was well-liked as a MDMA substitute in raves and club parties due to its minimal comedown and a clear, euphoric headspace. All six are now Schedule I controlled substances in the United States. [2] Phenethylamines listed [ edit ] Spontaneous bodily sensations - The "body high" of 2C-B is reported to be one of the most complex among psychedelics, exhibiting aspects of MDMA, 2C-E, and LSD. This is first characterized by an intense soft, warm glow that grows over the body and is capable of becoming highly euphoric.

However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive. I went into the book desiring mostly the second half, but fell in love with the first half as well. Shulgin is truly a genius and his way of viewing the world is touching and very powerful. The same goes for Ann. Many times while reading their story I found myself completely enraptured and falling in love with the both of them. One quote from Ann is one I intend to live my life by.The dosage of 2C-B is in the milligram region and the effects are highly dose dependent. There is a very steep dose response curve, which means that small changes to the dose that may be undetectable by eye could have drastic effects on the 2C-B experience. Alexander Shulgin states in PiHKAL that “over the 12 to 24 milligram range, every 2 milligrams can make a profound increase or change of response.” Therefore, it is critical that doses are measured accurately. B was first synthesized and tested for psychoactivity in 1974 by the American chemist and psychedelic researcher Alexander Shulgin, who was investigating novel psychedelic compounds based on the chemical structure of mescaline. It is important that you fully educate yourself on the health risks and drug interactions associated with 2C-B, and ensure that an accurate and suitable dose is consumed. 2C-B has some stimulant properties and therefore it is important to remain hydrated, especially if dancing. It is important to understand the metabolism of 2C-B by the body and the potential implications this may have. 2C-B is metabolised by enzymes called monoamine oxidases (MAOs) A and B, and therefore this could pose a risk for those on Monoamine Oxidase Inhibitors (MAOIs). This book makes specialist reading for anyone intrested in recreational drugs and organic chemistry. Currently there is a vast amount of misinformation about drugs in our society, particularly about ecstasy and designer drugs. Reading this book is a step in the right direction.

It’s important to note, the doses mentioned above were all ingested orally, which is the most popular way to take 2C-B. Folks report either swallowing a pill, weighing out their dose and mixing it with water, or “bombing” their dose by putting it in a rolling paper or piece of toilet paper, and swallowing it all like a pill. But nasal ingestion is also done, although many people warn that it is extremely painful—more so than with other substances. However, if you do choose to ingest nasally, doses should be significantly smaller because it comes on faster and stronger, and will also be shorter-lasting. 2C-B DurationThere is no current data for the LD 50 of 2C-B, but it is thought to be considerably higher than the active dose. Alexander Shulgin reported a 100 mg oral dose taken without apparent harm. [2] Dependence and abuse potential PiHKAL: A Chemical Love Story is a book by Dr. Alexander Shulgin and Ann Shulgin which was published in 1991. The subject of the work is psychoactive phenethylamine chemical derivatives, notably those that act as psychedelics and/or empathogen- entactogens. The main title is an acronym that stands for “Phenethylamines I Have Known and Loved”.

Verordnung des EDI über die Verzeichnisse der Betäubungsmittel, psychotropen Stoffe, Vorläuferstoffe und Hilfschemikalien" (in German). Bundeskanzlei [Federal Chancellery of Switzerland] . Retrieved January 1, 2020. Villalobos, C. A.; Bull, P.; Sáez, P.; Cassels, B. K.; Huidobro‐Toro, J. P. (2004). "4‐Bromo‐2,5‐dimethoxyphenethylamine (2C‐B) and structurally related phenylethylamines are potent 5‐HT 2A receptor antagonists in Xenopus laevis oocytes". British Journal of Pharmacology. 141 (7): 1167–1174. doi: 10.1038/sj.bjp.0705722 . eISSN 1476-5381. ISSN 0007-1188. OCLC 01240522. PMC 1574890 . PMID 15006903. When under the influence, do not make a phone call. Enjoy the inflated state if it happens and then leave or shut upI have more information regarding the universe and our reality in my MAJestic Index. You can see it here… MAJestic Articles & Links Similarly, in the Shulgins’ book PiHKAL, pleasant experiences are described in the 16 to 24 mg range, but harrowing and more challenging trips were occasioned by higher doses, such as this trip report authored by someone who took a 64 mg dose:

Users have reported experiencing hypertension, hyperthermia and tachycardia at higher doses. [19] As such, those with pre-existing heart conditions should avoid using 2C-B, and users monitor their temperature and heart-rate and respond accordingly. Heavy physical exertion while on 2C-B is discouraged. Betäubungsmittelgesetz (BtMG) § 29"[Narcotics Act (BtMG) § 29] (in German). Bundesamt für Justiz [Federal Office of Justice] . Retrieved December 10, 2019.I'm not going to write a traditional review of this book. Everyone has already done that. I AM going to try to describe what it has done for me.