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Journals

Because of the obvious limitations of conventional patch-clamp recording, the requirement of a massively parallelized, noninvasive, easy to control and high-precision intracellular recording platform (that is suitable for in vivo studies) motivates attempts to combine the present electrophysiological methods with nanotechnology. To date, nanotechnology has facilitated significant innovations in the areas of developing novel nanoscale electrical recording devices, characterizing the physiological status of recorded cells, and studying various interfaces between recording devices and the cell membrane. These changes represent the new progress of electrophysiology towards reliable, flexible, and efficient electrical recording from electrogenic cells. Design and production of electrical devices on the nanoscale Reinhold, K.; Lien, A.D.; Scanziani, M. Distinct recurrent versus afferent dynamics in cortical visual processing. Nat. Neurosci. 2015, 18, 1789–1797. [ Google Scholar] [ CrossRef] [ PubMed]