Dendrobium mixtures therapy not only changed gene expression patterns in type 2 diabetes but also improved immune activity and reduced the likelihood of cancer development. S

To the best of our knowledge, no anticancer treatment from Dendrobium herbs has been fully developed for instance. Thanks to scientific progress and awareness of factors related to life style, the population is becoming older. huoshanense reduced the levels of some cytokines associated with atopic dermatitis and had beneficial effects on symptoms.Its ability to attenuate migration and invasion in human lung cancer H23 cells was associated with an attenuation of endogenous reactive oxygen species (ROS), in which hydroxyl radical (OH•) was identified as a dominant species [ 32]. candidum extract would regulate the expression of AQP-5 in labial glands of SS patients and thereby promoted secretion of saliva to improve dry mouth symptoms [ 108]. This compound (3 µM) was found to be a potential anticancer agent for HRMPC by decreasing cellular glutathione, leading to a DNA damage response and cell cycle arrest at the S-phase. The sulfation occurred to C-2 and C-6 glucosyl residues seems also to be beneficial to enhance this activity [ 75]. nobile, decumbic acids A and B, (-)-decumbic acid, (-)- and (+)-dendrolactone, together with decumbic acid, 4-(3-hydroxyphenyl)-2-butanone, 3-hydroxy-1(3-methoxy-4-hydroxyphenyl)-propan-1-one and 3’,4’,5’-trimethoxycinnamyl acetate with IC50 values ranging from 15.

mL), whereas at the higher concentration tested (100 µg/mL) the leaves extract caused a significant increase in the extent of DNA damage, thus indicating a genotoxic effect. Target genes were mainly related to metabolic processes, cell growth, apoptosis, signal transduction, carbohydrate synthesis, carbohydrate degradation, transcription regulation, olfactory receptors, the microtubule system and the nervous system. w. on diabetic mice for 7 days, while DCP was orally administered at the concentration of 50-200 mg/kg b.trimethoxy-5,4’-dihydroxybibenzyl (DTB), aloifoll and 5,3’-dihydroxy-3,4-dimethoxy-bibenzyl, along with a lignin glycoside longicornuol A, from D. DP was found to consist of mannose, glucose, galactose, arabinose, xylose and glucuronic acid in the molar ratio of 10:0. Therapeutic roles of polysaccharides from Dendrobium Officinale on colitis and its underlying mechanisms.