You can get collagen through foods as well as dietary supplements. Research is ongoing as to the specific health benefits of collagen supplements versus food collagen. However, it’s clear that collagens add essential elements to your diet. Why You Need Collagens Alternatively, you can consume more vitamin C-rich foods, such as fruits and vegetables, to help naturally promote collagen synthesis. Is collagen keto-friendly? The most common animal collagen sources are human collagen, bovine, porcine, and marine organisms such as fish [ 24]. Despite the risk of bovine spongiform encephalopathy (BSE), bovine collagen is widely used in collagen-based products. The immune response to bovine collagen has been studied. A clinical study of 705 patients treated with a bovine collagen implant and a small percentage of patients had both the cellular and humoral types of the immune response [ 25]. Keefe, et al. showed that side effects to bovine collagen implants occurred in a small percentage of treated patients and these adverse reactions were resolved as the implant was resorbed by the patients [ 26]. Angiotensin-I converting enzyme (ACE) plays a key role in elevating blood pressure, and therefore, effective ACE inhibition can reduce blood pressure [ 27]. Bovine collagen is a promising precursor of ACE-inhibitory peptides in silico and in vitro protein digestions [ 28, 29]. The porcine collagen is widely used for extracting collagen as the bovine collagen. Porcine collagen does not cause much allergic response because it is almost similar to human collagen. Collagen peptides are promising for osteoporosis treatment and prevention. Porcine collagen peptides could be used to treat and prevent osteoporosis [ 30]. Porcine collagen membrane was tested in vitro and in vivo studies for guided bone regeneration [ 31]. The result indicated that the use of the porcine collagen membranes did not cause foreign body reactions and the porcine collagen membranes were biocompatible. A 2014 study in Skin Pharmacology and Physiology, excerpted in the National Center for Biotechnology In formation, gave a group of women aged 35-55 oral collagen peptides. At the end of the study, “skin elasticity in both CH dosage groups showed a statistically significant improvement in comparison to placebo. After 4 weeks of follow-up treatment, a statistically significantly higher skin elasticity level was determined in elderly women. ”

Bagheri Miyab K, Alipoor E, Vaghardoost R, Saberi Isfeedvajani M, Yaseri M, Djafarian K, Hosseinzadeh-Attar MJ. The effect of a hydrolyzed collagen-based supplement on wound healing in patients with burn: A randomized double-blind pilot clinical trial. Burns. 2020 Feb;46(1):156-163. doi: 10.1016/j.burns.2019.02.015. Epub 2019 Dec 16. PMID: 31859087. Some studies suggest that collagen supplements may help improve symptoms of osteoarthritis and reduce overall joint pain ( 8).

Finally, being mindful of what can damage collagen production is important. Such factors include excess sugar intake, smoking, sun exposure or ultraviolet light, and environmental pollutants. Treat these arguments with caution”. says Dr Mahto. “Evidence for the effectiveness of eating collagen on human skin outside of a lab is scarce, with little solid proof it will survive digestion, travel into the blood stream and make it to your skin. Most of the human studies have been carried out by the people selling the products, so there could be bias.” The effect of post-exercise protein supplementation with collagen peptides compared with placebo on the muscle mass and muscle function following resistance training of elderly sarcopenia patients was studied [ 75]. Additional dietary protein can increase the muscle protein synthesis rate after exercise and reduce the decomposition of muscle protein after resistance exercise. A total of 53 men with a mean age of 72.2 were recruited in the study. The results showed that 60 min of resistance exercise, performed three times per week, could significantly increase muscle mass, muscular strength, and motor control in sarcopenia patients. In addition, the study also showed that the combination of resistance exercise and collagen peptide supplementation resulted in a significant improvement in muscular strength as well as a significant increase in muscle mass and decrease in fat mass compared to placebo.

Gut health. Although no scientific evidence supports this claim, some health practitioners assert that collagen supplements can treat leaky gut syndrome, also called intestinal permeability.National Center for Biotechnology Information. PubChem Compound Summary for CID 656852, Glycyrrhizinate Dipotassium. Type I collagen – forms fibers and is found in connective tissue associated with bones, ligaments, tendons, and skin More research is needed to determine whether eating collagen-rich foods helps increase collagen levels in your body, as they may not have the same benefits as supplements. Collagen loss can also be accelerated by smoking, the sun, pollution, and a poor diet. As collagen production dips, the connective tissue between the skin becomes thinner and the layer of fat underneath it becomes more visible, leading to cellulite on the body. On the face, skin can become thinner and more fragile, and wrinkles may be more visible. Hair and nails can become weaker and joint pain may become more noticeable. Choi FD. Sung CT, Juhasz MLW, Mesinkovska NA. Oral collagen supplementation: A systematic review of dermatological applications. J Drugs Dermatol. 2019;18(1):9-16. PMID:30681787.

I ) , α 2 ( I ) , α 1 ( II ) , α 1 ( III ) , α 1 ( IV ) , α 2 ( IV ) , α 3 ( IV ) , α 4 ( IV ) , α 5 ( IV ) , α 6 ( IV ) , α 1 ( V ) , α 2 ( V ) , and α 3 ( V ) are proteins encoded by COL1A1, COL1A2, COL2A1, COL3A1, COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6, COL5A1, COL5A2 and COL5A3 genes, respectively. As the most abundant protein in the body, collagen is an important component of skeletal muscle ( 2). Researchers have suggested that supplemental collagen may promote the synthesis of muscle proteins such as creatine, as well as stimulate muscle growth after exercise ( NEW15). Formulyst’s Pro-Collagen Serum contains a highly concentrated mix of peptides and proteins, as well as hydrating hyaluronic acid formulated for aging skin. Apply a few drops of this hydrating serum to help skin look smoother and younger. Vital Proteins products are made in an NSF-certified, Current Good Manufacturing Practices (CGMP)-compliant facility and are free of:

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However, eating collagen-rich foods can help your body overcome some of this absorption problem. As a result, your body can stay stronger and healthier even as you get older. From the above discussions, compared with other drugs, collagen treatment has many advantages. However, it does not mean that the collagen treatment is absolutely safe. Some people may have an allergic reaction to collagen treatment. For example, some people may have a shellfish allergy and could experience anaphylaxis if they take marine collagen supplements. The other source of collagen may have an allergy problem. In a 6-month study, 31 healthy adults took 16 grams of collagen daily. They had experienced a significant reduction in measures of artery stiffness from the study’s beginning to its end ( 18). There are approximately 28 different types of collagen in the human body, but four are considered the most common. They are: Some older research suggests that vegan collagen could be produced using genetically modified yeast and bacteria. However, more studies are needed and vegan collagen supplements are not yet readily available.