Chan, J. M., Elkin, E. P., Silva, S. J., Broering, J. M., Latini, D. M., and Carroll, P. R. Total and specific complementary and alternative medicine use in a large cohort of men with prostate cancer. Urology 2005;66(6):1223-1228. View abstract. Gerber GS. Saw palmetto for the treatment of men with lower urinary tract symptoms. J Urol 2000;163:1408-12. View abstract. Descotes J, Rambeaud J, Deschaseaux P, and et al. Placebo-controlled evaluation of the efficacy and tolerability of Permixon in benign prostatic hyperplasia after exclusion of placebo responders. Clin Drug Invest 1995;9(5):291-297. Saidi S, Stavridis S, Stankov O, Dohcev S, Panov S. Effects of Serenoa repens alcohol extract on benign prostate hyperplasia. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2017;38(2):123-129. doi: 10.1515/prilozi-2017-0030. View abstract. Tracy TS. Saw palmetto. In: Tracy TS, Kingston RL, eds. Herbal Products. Toxicology and Clinical Pharmacology, Second Edition. Totowa NJ: Humana Press Inc.; 2007.

Marks LS, Tyler VE. Saw palmetto extract: newest (and oldest) treatment alternative for men with symptomatic benign prostatic hyperplasia. Urology 1999;53:457-61. View abstract.

How Much Saw Palmetto Should You Take?

MacLaughlin, B. W., Gutsmuths, B., Pretner, E., Jonas, W. B., Ives, J., Kulawardane, D. V., and Amri, H. Effects of homeopathic preparations on human prostate cancer growth in cellular and animal models. Integr.Cancer Ther 2006;5(4):362-372. View abstract. Busetto GM, Giovannone R, Ferro M,et al. Chronic bacterial prostatitis: efficacy of short-lasting antibiotic therapy with prulifloxacin (Unidrox®) in association with saw palmetto extract, lactobacillus sporogens and arbutin (Lactorepens®). BMC Urol. 2014;14:53. doi: 10.1186/1471-2490-14-53. View abstract.

Marks LS, et al. (2000). Effects of a saw palmetto herb blend in men with symptomatic benign prostatic hyperplasia [Abstract].Further research is needed before saw palmetto can be considered a suitable way to treat or prevent prostate cancer. Regulating testosterone Flamm, J., Kiesswetter, H., and Englisch, M. [An urodynamic study of patients with benign prostatic hypertrophy treated conservatively with phytotherapy or testosterone (author's transl)]. Wien.Klin.Wochenschr. 9-28-1979;91(18):622-627. View abstract.

Comar OB and Di Rienzo A. Mepartricina versus Serenoa repens: studio sperimentale doppio cieco su 20 casi di iperplasia prostatica benigna. Riv Ital Biol Med 1986;6(2):122-125. Gammoudi R, Ameur K, Ouni B, et al. Fixed drug eruption to Serenoa repens: first case report and consideration of the use of herbal medicine. Dermatol Ther 2020 Aug 29:e14247. View abstract. Löbelenz J. Extractum Sabal fructus bei benigner Prostatahyperplasie (BPH): Klinische Prüfung im Stadium I und II. Therapeutikon 1992;6(1-2):34, 37.

Does saw palmetto work?

The brand suggests that taking saw palmetto could promote male health by limiting hormones’ breakdown, thanks to the plant sterols, fatty acids, and flavonoids found in the supplement. Gerber GS, Zagaja GP, Bales GT, et al. Saw palmetto (Serenoa repens) in men with lower urinary tract symptoms: effects on urodynamic parameters and voiding symptoms. Urol 1998;51:1003-7. View abstract. They recommend adult men to take two capsules twice a day, preferably with a meal or mixed into a beverage, for best results. Aliaev, IuG, Vinarov, A. Z., Lokshin, K. L., and Spivak, L. G. [Efficiency and safety of prostamol-Uno in patients with chronic abacterial prostatitis]. Urologiia. 2006;(1):47-50. View abstract. Cheema P, El-Mefty O, Jazieh AR. Intraoperative haemorrhage associated with the use of extract of Saw Palmetto herb: a case report and review of literature. J Intern Med 2001;250:167-9. View abstract.

Cukier J, Ducassou J Le Guillou M Leriche A Lobel B Toubol J. [Permixon versus placebo; resultats d'une étude multicentrique]. Comptes Rendus deTherapeutique et de Pharmacologie Clinique. 1985;4:15-21. Saw palmetto has a range of uses. Most of them relate to the effect it is believed to have on testosterone. Cai, T., Mazzoli, S., Bechi, A., Addonisio, P., Mondaini, N., Pagliai, R. C., and Bartoletti, R. Serenoa repens associated with Urtica dioica (ProstaMEV) and curcumin and quercitin (FlogMEV) extracts are able to improve the efficacy of prulifloxacin in bacterial prostatitis patients: results from a prospective randomised study. Int.J Antimicrob.Agents 2009;33(6):549-553. View abstract. Wessagowit V, Tangjaturonrusamee C, Kootiratrakarn T, et al. Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract. Australas J Dermatol. 2016;57(3):e76-82. Testosterone esters (e.g., testosterone cypionate, testosterone enanthate, testosterone propionate, testosterone undecanoate, testosterone ester mixtures ( Deposterona, Omnadren, Sustanon, Testoviron Depot))

Ingredients & Allergens

Gurley BJ, Gardner SF, Hubbard MA, et al. In vivo assessment of botanical supplementation on human cytochrome P450 phenotypes: Citrus aurantium, Echinacea purpurea, milk thistle, and saw palmetto. Clin Pharmacol Ther 2004;76:428-40. . View abstract. Boyle P, Robertson C, Lowe F, Roehrborn C. Meta-analysis of clinical trials of permixon in the treatment of symptomatic benign prostatic hyperplasia. Urology 2000;55:533-9. View abstract. Hair loss is a common condition that can be caused by a variety of factors, including genetics, certain medical conditions, hormone changes, and the use of medications such as stimulants and blood thinners ( 1). Authie D and Cauquil J. Appreciation de l'efficacite de permixon en pratique quotidienne. [Appreciation of the in practice daily effectiveness of permixon]. C R Ther Pharmacol Clin 1987;5(56):4-13. Magri, V., Trinchieri, A., Pozzi, G., Restelli, A., Garlaschi, M. C., Torresani, E., Zirpoli, P., Marras, E., and Perletti, G. Efficacy of repeated cycles of combination therapy for the eradication of infecting organisms in chronic bacterial prostatitis. Int J Antimicrob.Agents 2007;29(5):549-556. View abstract.